idiopathic hypercalciuria is a leading cause of frequency-dysuria syndrome in childhood. different modes of inheritance have been suggested in this disease. this article presents the occurrence of idiopathic hypercalciuria in all children of two families. in the first family, a 5.5 year old girl with a history of renal stones and dysuria due to hypercalciuria, had two involved brothers and one ...

BACKGROUND AND OBJECTIVES This study aimed to determine the expression of osteoprotegerin, receptor activator of nuclear factor kappaB ligand, interleukin-1alpha, transforming growth factor-beta, and basic fibroblast growth factor in stone-forming patients with idiopathic hypercalciuria. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Immunohistochemical analysis was performed in undecalcified ...

BACKGROUND Idiopathic hypercalciuria is an important cause of symptoms related to the urinary system. The urinary excretion of high sodium and low potassium is a risk factor for hypercalciuria and urolithiasis. The aim of this study was to compare the urinary excretion of sodium and potassium by children older than two with idiopathic hypercalciuria and healthy control children in Bandar-Abbas,...

Idiopathic calcium nephrolithiasis and hypercalciuria are multifactorial disease conditions, the pathogenesis of which involves the interaction of environmental and individual factors. Data support a strong role of genes in the pathogenesis of these two conditions. Findings obtained in monogenic disorders characterized by renal calcium stones, and/or hypercalciuria, and/or nephrocalcinosis have...

PURPOSE Our aim was to determine association of vesicoureteral reflux (VUR) and idiopathic hypercalciuria in children with recurrent and single episode of urinary tract infection (UTI). MATERIALS AND METHODS The study group consisted of 45 children with VUR and recurrent UTI, and 2 control groups: 45 normal healthy children (control group 1) and 45 children with VUR and single episode of UTI ...

Idiopathic hypercalciuria (IH) is characterized by the excess excretion of calcium, despite normal levels calcium in blood and no apparent cause. In recent years, this metabolic disorder become more common to diagnose children can cause various urinary symptoms.

Flocks (1939) first noted an association between renal stone disease and increased calcium excretion in the urine, but it was not until 1953 that Albright, Henneman, Benedict & Forbes coined the term ‘idiopathic hypercalciuria’ to describe the disorder, suggested that it might be tubular in origin, and drew attention to the hypophosphataemia which frequently accompanies it. A few years later He...