imbalanced immune responses against fetus alloantigens can lead to abnormality in pregnancy. interleukin-10(il-10) plays key roles in regulation of immune responses against self and foreign antigens to induce tolerance to these antigens. therefore, alteration in expression of il-10 during pregnancy may result in several pathologic conditions such as preterm labor. il-10 leads to a normal pregna...

conclusions the mir-155 appeared to be suppressed during hbv infection. the significantly higher mir-155 levels in alt-elevated patients infected with hbv suggest that mir-155 levels in pbmcs correlate with the immune state of patients with chronic hbv infection. results in the hbv-infected patients, the mir-155 levels were significantly lower than in the healthy controls (p = 0.001). chronic h...

Background: Aging is associated with attenuation of immune responses. Studies show that old people are vulnerable to infectious diseases such as influenza. α-Tocopherol as an immunomodulator affects immune responses. In the present study, the effect of α-tocopherol, on lymphocyte responses i.e. interferon-gamma (IFN-γ), Tumor Necrosis Factor-alpha (TNF-α), and nuclear factor-κB (NF-κB)  in elde...

objective(s): drug delivery via mucosal routes has been confirmed to be effective in inducing strong immune responses. liposomes could enhance immune responses and mucoadhesive potentials, make them useful mucosal drug delivery systems. coating of liposomes by mucoadhesive polymers succeeded in enhancing immune responses. our studies aim at preparation and characterization of trimethylchitosan-...

Background: Long-term and intensive physical exercise can change the function of different cells in the immune system in athletes, predisposing them to viral infections such as coronavirus disease (COVID-19). The purpose of this brief report was to provide protocols related to the immune system in athletes to prevent infectious diseases. Methods: To examine immune system res...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 aim : in this study we co-administered melittin along with hbsag/alum vaccine to investigate if it helps elicitation of th1/th2 response. background : hepatitis b virus (hbv) infection is a life-threatening liver infection, which can lead to chronic l...

Atherosclerosis is a complex inflammatory disorder of the medium and large-sized arteries. Recent experiments demonstrated that atherosclerosis is a Th1 dominant autoimmune condition, whereas Th2 cells are rarely detected within the atherosclerotic lesions. Several studies have indicated that Th2 type cytokines could be effective in the reduction and stabilization of atherosclerotic plaque. The...