Autogenic embryonic stem cells established from somatic cell nuclear transfer (SCNT) embryos have been proposed as unlimited cell sources for cell transplantation-based treatment of many genetic and degenerative diseases, which can eliminate the immune rejection that occurs after transplantation. In the present study, pluripotent nuclear transfer ES (NTES) cell lines were successfully establish...

The stochastic dynamics of a two-state bioreactor model with random feed flow fluctuations and non-monotonic specific growth rate is analyzed. Using the Fokker-Planck equation approach for describing probability density function (PDF) evolution lack robustness due to deterministic bifurcation phenomena open-loop reactor operating under optimal (maximum production) operation condition establishe...

Extended abstract Understanding the complexity of the fluid dynamics in bubble column and airlift reactors is important due to their application in the chemical and bioprocess industries. So the objective of this research was to develop a fundamental understanding of the hydrodynamics and interactions with the chemistries involved in the bubble column reactor to maximize overall efficiency for ...

The performance stability and its recovery mechanisms of a partial nitritation-anammox process were investigated. A one-stage airlift enhanced micro-granules (AEM) system was operated for 650 days continuously to treat 50 mg-NH4/L wastewater. During the stable stage, high nitrogen removal efficiency 72.7 ± 8.4% lasting 230 successfully achieved under 0.28 L/min aeration rate 0.10–0.20 mg/L diss...

Efficient allocation of aircraft and aircrews to transportation missions is an important priority at the USAF Air Mobility Command (AMC), where airlift demand must increasingly be met with less capacity and at lower cost. In addition to presenting a formidable optimization problem, the AMC resource management problem is complicated by the fact that it is situated in a continuously executing env...

In this study, granulated sludge synthesized in a sequence batch reactor (SBR) and then granulated sludge was transferred to continuous feeding and intermittent discharge (CFID) bioreactor. Two independent variables (air flow rate and hydraulic retention time (HRT)) were considered to optimize the process. Subsequently, long term performance (150 days) of the bioreactor was assessed by monitori...

Immune thrombocytopenic purpura (ITP) is an autoimmune disease that affects thousands of Americans each year. The resulting thrombocytopenia, which develops from destruction of platelets (PLT) by anti-PLT autoantibodies (APAb), is often associated with hemorrhagic complications. Existing therapies are not effective and are associated with significant morbidity. Recently, a new treatment modalit...