background : there is an association   of celiac disease (cd) with several gastrointestinal illnesses. we aimed to determine   the prevalence of cd in patients with inflammatory bowel disease (ibd) to evaluate the value of the routine serological tests for cd in these patients. methods : patients with ibd underwent   screening test for cd. the screening test was based on iga anti-ttg antibody e...

conclusions exercise can improve anthropometric variables, body composition and vo2 peak and reduce some inflammatory markers in breast cancer survivors. objectives the current study aimed to investigate the effect of eight weeks of training on il-6, tnf-α and hcrp in postmenopausal breast cancer survivors. patients and methods twenty-seven postmenopausal breast cancer survivors with mean age o...

Objective(s): Naringin, an essential flavonoid, inhibits inflammatory response and oxidative stress in diabetes. However, whether naringin has beneficial effects on diabetic retinopathy (DR) remains unknown. Materials and Methods: Streptozotocin (STZ, 65 mg/kg) was intraperitoneally injected into male rats (8 weeks old weighting 200-250 g) to establish diabetic model, then naringin (20, 40 or 8...

rheumatoid arthritis (ra) is a chronic inflammatory disorder characterized by joint swelling, synovial inflammation and joint destruction. curcumin (diferuolymethane) is the most active component of curcuma longa l. several clinical trials have indicated curcumin to be a notable anti-inflammatory and antioxidant compound. therefore the aim of this study is investigating the effects of curcumin ...

background: given widespread deleterious health effects of an augmented inflammatory state, identification of therapies that reduce inflammation is critical. the purpose of the present study was to investigate the effects of 10 weeks endurance training on pro-inflammatory cytokines and their relationships with cortisol and testosterone hormones in sedentary young men. methods: twenty sedentary ...

Non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat acute and chronic pain associated primarily with inflammatory changes. This group of is widely in neurology, rheumatology, traumatology, etc. The main mechanism action the effect on cyclooxygenase-2 (COX-2) blockade synthesis pro-inflammatory prostaglandins (PG), as well COX-1 suppression cytoprotective PG, which determines possib...

periodontal disease is a chronic inflammatory disease which represents a primarily anaerobic gram‑negative oral infection that results in gingival inflammation, loss of attachment, bone destruction. bacterial endotoxins in the form of lipopolysaccharides (lps) that are instrumentalin generating a host‑mediated tissue destructive immune response by mobilizing their defensivecells and releasing c...

non-steroidal anti-inflammatory drugs (nsaids) are the most common pharmacological group that has three primary therapeutic effects including anti-inflammatory, anti-pyrexia, and analgesia. in this study, seven of nsaids were tested against two species of skin pathogenic fungi (dermatophytes). percentage inhibition was determined for effective agents. diclofenac, aspirin and naproxen showed muc...

Berberis vulgaris L (B. vulgaris) and its main constituent berberine have been used in traditional medicine for a long time. This medicinal plant and berberine have many properties that have attracted the attention of researchers over the time. According to several studies, B. vulgaris and berberine exhibited anti-inflammatory, antioxidant, anticonvulsant, antidepressant, anti-Alzheimer, anti-c...

For many years, cyclooxygenase-2 (COX-2), a critical enzyme for PG production, has been the favorite target for anti-inflammatory drug development. However, recent revelations regarding the adverse effects of selective COX-2 inhibitors have stimulated intense debate. Interestingly, in the early phase of inflammation, COX-2 facilitates inflammatory PG production while in the late phase it has an...