background: approximately 180 mutations have been described in β-thalassemia worldwide with specific spectrum in each ethnic population. this study determines the spectrum and the frequency of β-thalassemia mutations in patients with β-thalassemia trait and sickle cell-β-thalassemia.   methods: fifteen compound heterozygous sickle cell thalassemia (sct) and 23 β-thalassemia trait patients were ...

the most important characteristic of dome and factors influencing it in the islamic iranian architecture that is different from other courses is construction and construction methods of them. over time, different factors are involved in the process of formation of the domes. it is one of the factors influencing the structure of iranian-islamic domes. by examining the structure of iranian-islami...

the current study attempts to revise the curriculum and syllabus of the basic design studios in undergraduate program of architecture. the current curriculum has been executed since 1999 in iran. in this program lasting for eight to nine semesters, three semesters is dedicated to basic design education, which is workshop-base. despite the proposed curriculum for these studios, the accurate and ...

We have isolated a myeloma genomic DNA clone containing the variable and constant regions of a mouse alpha chain. Restriction enzyme analyses and electron microscopic R loop mapping have demonstrated that the variable region is separated from the constant region by 6.8 kilobases of intervening DNA. In addition, two intervening DNA sequences of 100--200 bases separate the constant region into th...

DNA-templated organic synthesis (DTS) enables new modes of controlling chemical reactivity and allows evolutionary principles to be applied to the discovery of synthetic small molecules, synthetic polymers, and new chemical reactions. The structures that can be accessed in a DNA-templated format thus far have been limited to those that can be generated in aqueous solvents. Here we report effici...

This issue of the Journal describes potential for such changes to lower probability firearm-related injuries and fatalities, not just children adolescents, but persons all ages.

contemporary architecture by symbolic and visual design creates an image in the minds of tourists so that these images are then converted to urban brands. combining symbolic monuments and modern buildings in the world today is a promising development of cities in many municipalities, municipalities and government agencies to freely and without regard to the needs of their local employs all the ...

Glancing through the contemporary architecture of Iran and its different generations during the Pahlavi era, it seems that there have been notions and ideas regarding the architecture which can be considered as a specific current in the architecture of Iran based on different elements of architecture criticism; then the aim of this study is to scrutinize those notions and ideas and their transf...