Durations of intravenous antibiotic therapy for bacterial infections in hospitalized children sometimes extend well beyond clinical recovery and are often the primary determinants of length of stay. These durations, however, are not always based on solid evidence. Moreover, fixed durations are invariant to important individual factors. We review guidelines and the available evidence for duratio...

BACKGROUND Neutropenic fever is one of the most serious adverse effects of cancer chemotherapy. Neutropenia may cause a life-threatening bacterial infection. Therefore, febrile neutropenic inpatients are empirically treated with intravenous broad-spectrum antibiotics. Recently, several studies have suggested the presence of low-risk groups among febrile neutropenic patients. METHODS A prospec...

In children with severe bacterial infection in low-resource settings, switch from intravenous to oral antibiotics is important reduce nosocomial infections and costs. We report barriers reliable antibiotic administration under five admitted Kisantu hospital (DR Congo) bloodstream infection. Qualitative observations were compiled during field studies (DeNTS/TreNTS study: NCT04473768 /04850677). ...

abstract objective fever and neutropenia are a common complication of chemotherapy in cancer. it is usually managed by hospitalization and empiric administration of antibiotics. use of fluroquinolones is limited because of joint/cartilage toxicity. this study attempted to compare the efficacy of oral ciprofloxacin with intravenous ceftazidim in low risk febrile neutropenic lymphocytic leukemia....

BACKGROUND Pyogenic spondylodiscitis is a form of spinal infection that can result in severe back pain and even death. However, information is lacking on the relative effectiveness of various therapies. A retrospective chart review was conducted to investigate whether early surgical treatment of pyogenic spondylodiscitis coupled with intravenous antibiotics results in better patient prognoses t...

Abstract Introduction Diverticular disease is a common surgical problem ranging from diverticulosis to uncomplicated diverticulitis complicated diverticulitis. The NICE Guidelines for diverticular recommended that antibiotics should only be given in patients who are systemically unwell, background of immunosuppression or have We aimed access the compliance these guidelines with regards use at o...