introduction septic cavernous sinus thrombosis (cst) is a rare condition that can result in high mortality and morbidity rates if not treated immediately. cst may be aseptic or septic. less common primary sites of infection include the tonsils, soft palate, middle ear, and orbit. reported cases of middle ear infection are very rare, and response to treatment is poor. conclusions findings of lab...

OBJECTIVE The aim of the study was to review evidence-based data regarding the use of antibiotics for the treatment of appendicitis in children. DATA SOURCE Data were obtained from PubMed, MEDLINE, and citation review. STUDY SELECTION We conducted a literature search using "appendicitis" combined with "antibiotics" with children as the target patient population. Studies were selected based ...

We believe that prompt initiation of eradication protocols for new Pseudomonas aeruginosa infection and early, high dose intravenous antibiotic treatment of respiratory exacerbations have been the most important factors responsible for the improved outlook for people with CF (Conway et al, 1985; Smith et al, 1988; Regelmann et al, 1990; Bradley et al, 1999). All patients require regular respira...

Intravenous antibiotics effectively reduce the prevalence of postoperative infection. However, Japanese orthopaedic surgeons have no consensus with regard to the optimal duration of prophylaxis. The aim of this study is to compare the outcome of one-day intravenous antibiotic administration with that of long-term intravenous antibiotic administration. Patients who underwent total hip or knee ar...

OBJECTIVES There is a subset of patients with chronic rhinosinusitis (CRS) that demonstrate osteitis of the sinuses. Osteitic bone is evident on computed tomography (CT) as hyperostosis. We propose treatment of this entity with a six week course of outpatient intravenous antibiotics in an approach similar to that used in the orthopedic literature for long bone osteomyelitis. This group of patie...

BACKGROUND The use of oral prophylactic antibiotics for the prevention of surgical-site infection (SSI) in patients undergoing laparoscopic surgery for colorectal cancer is controversial. The aim of this RCT was to evaluate whether intravenous perioperative antibiotics are inferior to combined preoperative oral and perioperative intravenous antibiotics in this setting. METHODS Patients underg...

Pulmonary exacerbations in adults with cystic fibrosis (CF) and chronic (Psae) infection are usually treated with dual Pseudomonas aeruginosa intravenous antibiotics for 14 days, despite the lack of evidence for best practice. Intravenous antibiotics are commonly associated with various systemic adverse effects, including renal failure and ototoxicity. Inhaled antibiotics are less likely to cau...