Campylobacter jejuni is a major cause of food-borne disease in industrialized countries. Carbohydrate utilization by C. jejuni is severely restricted, and knowledge about which substrates fuel C. jejuni infection and growth is limited. Some amino acids have been shown to serve as carbon sources both in vitro and in vivo. In the present study we investigated the contribution of serine and prolin...

Recent applications of high-field NMR spectroscopy in biosynthesis will be discussed. The emphasis of the lecture will be on the use of 1H, 3H, '3C and '5N-NMR to focus on individual steps of biochemical processes in the formation of natural products and related enzyme-catalyzed events. In the first set of experiments, pulse labelling and invivo studies are used to uncover biosynthetic sequence...

immediate early step in PrE specification. We show that the fraction cells present with in this state is influenced by factors that both promote and suppress primitive PrE differentiation, however conditions that support ES cell self-renewal prevent their progression into endoderm differentiation and support an equilibrium between this state and at least one other that resembles the inner cell ...

In this paper, the discrete wavelet packet frames are used to delineate the atherosclerotic plaque components using intravascular ultrasound (IVUS) backscattered signals. The frames are classified in an unsupervised fashion deploying K-means clustering technique and the generated prognosis histology (PH) images are quantified using relative histology images. While existing tissue characterizati...

The cotton bollworm, Helicoverpa armigera is a polyphagous pest and causes oxidative damage to field crops. Salicylic acid is the cell signaling molecule produced in response to insect attack on plants. Catalase plays a major role in the protection of tissues from the toxic effects of H2O2 and partially reduced oxygen species. Invitroand Invivo effect of salicylic acid was studied on the activi...

immediate early step in PrE specification. We show that the fraction cells present with in this state is influenced by factors that both promote and suppress primitive PrE differentiation, however conditions that support ES cell self-renewal prevent their progression into endoderm differentiation and support an equilibrium between this state and at least one other that resembles the inner cell ...

BACKGROUND H9N2 avian influenza viruses continue to spread in poultry and wild birds throughout Eurasia. OBJECTIVES To characterize H9N2 influenza viruses from pheasants, quail, and white-bellied bustards (WBBs) used to train falcons in the United Arab Emirates (UAE). METHODS Four H9N2 viruses were isolated from pheasants, quail, and WBB used for falconry in the UAE, and antigenic, molecula...

Melatonin is known to influence a variety of biological processes including circadian rhythms, neuroendocrine, and cardiovascular and immune functions as well as thermoregulation. Melatonin is the chief secretory product of the pineal gland, although it is also produced in other organs. In this study, in vitro effects of melatonin on 6-phosphogluconate dehydrogenase from human erythrocytes and ...

Traditionally, drugs are discovered by testing compounds synthesized in time consuming multi-step processes against a battery of invivo biological screens. Promising compounds are then further studied in development, where their pharmacokinetic properties, metabolism and potential toxicity were investigated. Here, we present a study on herbal lead compounds and their potential binding affinity ...