نتایج جستجو برای: lch
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Langerhans cell histiocytosis (LCH) combines in one nosological category a group of diseases that have widely disparate clinical manifestations but are all characterized by accumulation of proliferating cells with surface markers and ultrastructural features similar to cutaneous Langerhans cells (LCs). In particular, careful molecular analyses of mouse models and human LCH samples suggest that ...
UNLABELLED Histiocytic neoplasms are clonal, hematopoietic disorders characterized by an accumulation of abnormal, monocyte-derived dendritic cells or macrophages in Langerhans cell histiocytosis (LCH) and non-Langerhans cell histiocytosis (non-LCH), respectively. The discovery of BRAF(V600E) mutations in approximately 50% of these patients provided the first molecular therapeutic target in his...
Background Langerhans cell histiocytosis (LCH) is a rare disorder of the reticuloendothelial system with unknown etiology. This report aims to present a case of LCH with diffuse involvement of the oral cavity and to raise awareness of the distinguishing features of this diagnostically challenging entity. Case Report A 26-year-old male patient presented with complaints of teeth mobility, inten...
Langerhans cell sarcoma (LCS) is a neoplastic proliferation of Langerhans cells that have overtly malignant cytologic features. It is a very rare disease and theoretically, it can present de novo or progress from an antecedent Langerhans cell histiocytosis (LCH). However, to our knowledge, LCS arising from an antecedent LCH has not been reported on. We present here a case of LCS arising from a ...
To cite: Khoo ABS, Garioch J. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2016217904 DESCRIPTION A woman aged 80 years was admitted under the general physicians with a 2-week history of general malaise. She was referred to dermatology for an opinion on a rash which had been present for 6 months. Examination revealed an erythematous, keratotic and papular rash ...
BACKGROUND We wished to evaluate the treatment methods for vertebral Langerhans cell histiocytosis (LCH) (a rare reticuloendothelial disorder) at a tertiary care pediatric centre and compare treatment and outcomes with those reported in the recent literature. METHODS A total of 55 charts were retrieved between 1980 and 2003 for children with LCH. Only those children who were under 18 years of...
Langerhans cell histiocytosis (LCH) is a rare histiocytic neoplasm. The clinical presentation and the disease extension are variable. LCH may involve single site, multiple sites within system, or systems. Gastrointestinal tract involvement most often observed in children with multisystem disease. Adult patients gastrointestinal extremely rare, only few cases have been reported. We present 45-ye...
This article offers a history of the English legal category monster, a legal category that entered English law in the mid-thirteenth and survived until the mid-nineteenth century. The aim of the article is to provide a close textual analysis of an otherwise absent legal history and to locate law’s monsters, and the anxieties that they suggest, within their appropriate contexts: social, politica...
Here I summarize some of the salient features of technicolor theories with technifermions in higher dimensional representations of the technicolor gauge group. The expected phase diagram as function of number of flavors and colors for the two index (anti)symmetric representation of the gauge group is reviewed. After having constructed the simplest walking technicolor theory one can show that it...
Histiocytosis is a term applied to a group of rare disorders of the reticuloendothelial system. Eosinophilic granuloma is the most benign and localized of the three Langerhans cell histiocytosis (LCH) entities that could be solitary or multiple. In 2015, the incidence of the disease was reported to be 1 in 9100000. Eosinophilic granuloma can affect almost any bone, but commonly involves the man...
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