نتایج جستجو برای: licensing agreement

تعداد نتایج: 173129  

Journal: :BMJ 1986

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Journal: :BMJ 2002

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Journal: :The RAND Journal of Economics 2018

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Journal: :Nature Biotechnology 2002

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Journal: :SSRN Electronic Journal 2018

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Journal: :Journal of Criminal Law and Criminology (1931-1951) 1945

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Journal: :International Free and Open Source Software Law Review 2012

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Journal: :Academic Medicine 1931

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2013
Yongxin Zou Jun Mi Wenxing Wang Juanjuan Lu Wei Zhao Zhaojian Liu Huili Hu Yang Yang Xiaoxing Gao Baichun Jiang Changshun Shao Yaoqin Gong

Cullin-RING ubiquitin ligases (CRLs) participate in the regulation of diverse cellular processes including cell cycle progression. Mutations in the X-linked CUL4B, a member of the cullin family, cause mental retardation and other developmental abnormalities in humans. Cells that are deficient in CUL4B are severely selected against in vivo in heterozygotes. Here we report a role of CUL4B in the ...

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Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Yoshinori Ohno Shin'ichiro Yasunaga Motoaki Ohtsubo Sayaka Mori Miyuki Tsumura Satoshi Okada Tomohiko Ohta Kiyoshi Ohtani Masao Kobayashi Yoshihiro Takihara

Retrovirus-mediated transduction of Hoxb4 enhances hematopoietic stem cell (HSC) activity and enforced expression of Hoxb4 induces in vitro development of HSCs from differentiating mouse embryonic stem cells, but the underlying molecular mechanism remains unclear. We previously showed that the HSC activity was abrogated by accumulated Geminin, an inhibitor for the DNA replication licensing fact...

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