1. Highly purified preparations of glucoamylase were obtained from liver, spleen and intestine of the monkey. The enrichment factor was lower for intestine (60-fold) compared with that of liver (1200-fold) and of spleen (2000-fold) but the final specific activities were of a similar magnitude. 2. The liver and spleen enzymes had maximum activity at pH4.8 whereas the intestinal enzyme showed an ...

Background and Aim: Non-alcoholic fatty liver disease (NAFLD) is recognized as a metabolic liver disease in the world. The purpose of this study was to investigate the preventive effects of Punica granatum extract on fatty liver disease in the rats receiving high fat diet. Material and Methods: In this study rats were divided into 6 groups: healthy control, feeding with high fat diet, feeding ...

Background: Studies have shown that organophosphorus pesticides such as malathion induces oxidative stress injury and tissue damage.  Objectives: This research aimed to determine the effects of the hydroalcoholic extracts of Satureja avromanica (SA) on the liver function of malathion-poisoned animals. Methods: Twenty-eight rats were divided into four groups of the control, SA (20 mg/kg), mala...

The present study was conducted to investigate the expression level of cytochrome P450 enzyme in detoxification of water soluble fractions (WSFs) of crude oil in Persian sturgeon, Acipenser persicus. Fish were exposed to WSFs at concentrations of 0 (control), 10, 20, and 50% of the LC50 for 14 days, and then, the expression level of P450 gene was assayed in gill and liver samples. According to ...

introduction: the fate of xenobiotics that is present, increasing day by day. the increasing fates altered or inhibit the metabolic activities like detoxification and biotransformation. methods: the present study highlights this slow biotransformation and detoxification on the basis of specific enzymes which have a say in assessment of mercuric chloride toxicity and modulation by panax ginseng ...

The global pandemic COVID-19, caused by SARS-CoV-2, affected millions of people. COVID-19 is known for its respiratory symptoms, but new research reveals it may also affect other organ systems, including the liver. This abstract reviews and liver function. virus enters host cells through liver-expressed angiotensin-converting enzyme 2 (ACE2) receptors. Thus, viral infection replication target V...

common cancer and the third leading cause of cancer-related deaths. A known risk factor for HCC is non-alcoholic fatty liver disease (NAFLD), a continuum hepatic disorders related to obesity metabolic syndrome. AIM: We conducted an observational study identify factors hepatocellular in patients with who came SMHRC Nagpur routine visit. MATERIAL AND METHODS: The included 300 people aged 35 85 ye...

Cholinesterase (ChE) is a group of enzymes that hydrolyze cholinester. There are two ChE isoenzymes in the blood, namely Acetylcholinesterase (AChE) and Butyrylcholinesterase (BChE). Both required process sending nerve signals. The activity these will be decreased by exposure to toxic chemical agents, insecticides such as organophosphates or carbamates, anesthetic drug therapy for Alzheimer’s d...

Evidence is presented that there is a considerable accumulation of inactive fructose-1,6-diphosphate aldolase (EC 4.1.2.7) in the liver of senescent mice. Liver aldolase was purified from 3-month-old mice and used to immunize rabbits. It was demonstrated with the monospecific antibody thus produced that the liver aldolase of young adult (3 month) and aged (31 month) mice are antigenically ident...

Lysophosphatidic acid (LPA) is an endogenous lysophospholipid and a bioactive lipid that synthesized by the enzyme autotaxin (ATX). The ATX–LPA axis has been associated with cognitive dysfunction inflammatory diseases, mainly in range of nonalcoholic liver diseases. Recently, preclinical clinical evidence suggested role LPA signaling alcohol use disorder (AUD) AUD-related function. However, not...