نتایج جستجو برای: lm convergence space
تعداد نتایج: 605264 فیلتر نتایج به سال:
In continuation of our efforts toward the discovery of potent HIV-1 NNRTIs with novel structures, we have employed a scaffold hopping strategy to explore the chemically diversed space of bioactive compounds. The original arylazolylthioacetanilide platform was replaced with different imidazopyridinylthioacetanilide scaffolds to yield the optimal pharmacophore moieties in order to generate novel ...
In this thesis, a special class of Recurrent Neural Networks (RNN) is employed for system identification and predictive control of time dependent systems. Fundamental architectures and learning algorithms of RNNs are studied upon which a generalized architecture over a class of state-space represented networks is proposed and formulated. Levenberg-Marquardt (LM) learning algorithm is derived fo...
We show that the category of convergence approach spaces is a simultaneously reective and coreective subcategory of the category of latticevalued limit spaces. Further we study the preservation of diagonal conditions, which characterize approach spaces. It is shown that the category of preapproach spaces is a simultaneously reective and coreective subcategory of the category of lattice-valued p...
We describe the clinical and therapeutic course of a 51-year-old woman with HER-2+ breast cancer who developed leptomeningeal (LM) and spinal cord metastases after 8 years of stable disease on combination therapy with intravenous (IV) trastuzumab. Due to progressive CNS disease, intrathecal (IT) trastuzumab was introduced to enhance HER-2+ therapy into the CSF space. A combination HER-2+ target...
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