In the oxyntic mucosa of the mammalian stomach, histamine is stored in ECL cells and in mucosal mast cells. In the rat, at least 80 percent of oxyntic mucosal histamine resides in the ECL cells. Histamine is a key factor in the regulation of gastric acid secretion. Following depletion of ECL-cell histamine by treatment with alpha-fluoromethylhistidine (alpha-FMH), basal acid secretion was reduc...

This paper provides a review of the Fractal Market Hypothesis (FMH) focusing on financial times series analysis. In order to put FMH into broader perspective, Random Walk and Efficient Hypotheses are considered together with basic principles fractal geometry. After exploring historical developments associated different hypotheses, an overview mathematical modelling is provided. The principal go...

reduction in maternal mortality requires an in-depth knowledge of the causes of death. this study was conducted to explore the circumstances and events leading to maternal mortality through a holistic approach. using narrative text analysis, all documents related to maternal deaths occurred from 2007 to 2011 in kerman province/iran were reviewed thoroughly by an expert panel. a 93-item chart ab...

Hypertensive disorders are one of the most common medical complications of pregnancy and a major cause of both maternal and fetal morbidity and mortalityand are one of the leading causes of maternal deaths.1-4 They can cause several dreaded complications such as eclampsia, disseminated intravascular coagulation, cerebral edema, liver failure and ante-partum hemorrhage. Maternal hypertension als...

Mirror syndrome is a rare clinical entity consisting of fetal and placental hydrops with maternal edema. It is associated with an increase in fetal mortality and maternal morbility. We describe the anesthetic management of a parturient with Mirror syndrome complicated by HELLP syndrome and massive postpartum hemorrhage, who required general anesthesia for cesarean delivery.

BACKGROUND Auditing of sentinel health events based on best-practice protocols has been recommended. This study describes a population-based investigation on adverse perinatal events including severe acute maternal morbidity (near-miss), maternal and perinatal mortality, as a health intervention to help improve the surveillance system. METHODS From October to December 2005, all cases of mater...

Trauma affects up to 6% to 7% of all pregnancies, and accounts for up to 46% of maternal death. Adverse consequences such as preterm labor and delivery, abruptio, fetomaternal hemorrhage, and fetal demise may be seen with even apparently minor degrees of injury. Maternal physiologic considerations are reviewed and a protocol for evaluation and management of the injured gravida is presented.

BACKGROUND Most maternal deaths occur in developing countries and most maternal deaths are avoidable. China has made a great effort to reduce MMR by three quarters to meet the fifth Millennium Development Goal (MDG5). METHODS This retrospective study reviewed and analyzed maternal death data in Wuhan from 2001 to 2012. Joinpoint regression and multivariate Poisson regression was conducted usi...