Very few studies have shown associations between autism spectrum disorder, attention deficit hyperactivity disorder and Chiari 1 malformation. Here, we report an 10-year-old male that presented after having seizures with a history of Chiari 1 malformation, autism spectrum disorder and ADHD with moderate mental retardation and speech delay. This case highlights the fact that autism spectrum diso...

Factors influencing early hospital admission have been described for several stroke types but not for cerebral vein and dural sinus thrombosis (CVT). CVT is more difficult to diagnose than arterial stroke; delay in hospital admission may postpone CVT treatment. The purposes of this study were: (1) to describe the delay between the onset of symptoms and hospital admission of patients with CVT, a...

how to cite this article: firoozeh sajedi f, ahmadi doulabi m, vameghi r, mazaheri ma, akbarzadeh baghban ar. relationship of mothers’ psychological status with development of kindergarten children. iran j child neurol. summer 2016; 10(3):61-72.   abstract objective given the importance of children’s development and the role of psychological status of mothers in this regard, this study investig...

Rapid advances in neonatal care have led to a dramatic surge in survival of the veryand extremely-premature infants. This is, however ,tempered by a concomitant increase in the incidence of severe neuromorbidity in the survivors, including cognitive delay, cerebral palsy, hearing loss, blindness, mental retardation, and epilepsy. Thus, an emerging challenge in newborn care is to translate the g...

Cornelia de Lange syndrome (CdLS) is a multisystem malformation syndrome. There is wide clinical variability in this disorder. This disorder is relatively uncommon and characterised by series of malformations which includes skeletal, craniofacial, gastrointestinal and cardiac malformations. The main clinical feature includes growth retardation, limb abnormalities, mental retardation, developmen...

Pachygyria is a disorder of neuronal migration. We report an Indian family with four siblings with developmental delay, infrequent seizures, normal head size and mild to moderate mental retardation. Two of them had bilaterally symmetrical frontotemporal pachygyria. Dysmorphism and neurological signs were absent in the affected subjects. Affected male and female siblings with normal parents sugg...

A 6-year-old boy with speech delay and mild mental retardation (IQ 82) was found to have a complex double translocation involving four chromosomes and a total of five breakpoints, two being on the same arm. This resulted in the karyotype 46,XY,t(2;4;7)(7;8)(q14;q31;q11q22;q13). As far as the authors are aware this is the first time that such a complex double translocation has been reported. Bot...

We describe a new creatine metabolism disorder in 2 young sisters who suffered from mental retardation and severe language delay. Blood examination, investigation of the most common neurometabolic disorders, and brain magnetic resonance imaging were normal. Diagnosis was established only by means of in vivo proton magnetic resonance spectroscopy, which disclosed generalized depletion of creatin...

Functional MRI produces a more accurate localization of the language areas for epilepsy surgery purpose, but requires the patient's cooperation. We report a 34 year-old woman with mental retardation who underwent two different verbal fluency tasks, category and word naming. We found a strong activation of Broca's area in the most difficult task. We suggest that a multi-task fMRI study could be ...