OBJECTIVE Plasma adiponectin is strongly associated with various components of metabolic syndrome, type 2 diabetes and cardiovascular outcomes. Concentrations are highly heritable and differ between men and women. We therefore aimed to investigate the genetics of plasma adiponectin in men and women. METHODS We combined genome-wide association scans of three population-based studies including ...

Na udruženost različitih metaboličkih poremećaja kao što su povišeni nivo šećera u krvi, hipertenzija i giht prvi je ukazao švedski doktor Kylin 1 dvadesetih godina prošlog veka. Pre nešto više od pola veka Vague 2, 3 iz Marseillea ukazao je da na visok rizik za pojavu bolesti krvnih sudova utiče ne samo količina nego i raspodela masti (androgeni, muški tip gojaznosti). Deset godina kasnije, 19...

The metabolic syndrome is a cluster of metabolic disorders, such as abdominal obesity, dyslipidemia, hypertension and impaired fasting glucose that contribute to increased cardiovascular morbidity and mortality. Although the pathogenesis of metabolic syndrome is complicated and the precise mechanisms have not been elucidated, dietary lipids have been recognized as contributory factors in the de...

background: despite the great impact of diet on the metabolic syndrome, limited data are available relating dietary energy density to this syndrome. furthermore, due to specific characteristics of diet in middle-eastern countries, looking for the association between dietary energy density and metabolic syndrome in this part of the world would be interesting. this study was performed to assess t...

Introduction: Transient hyperglycemia is a condition that happens during acute physiologic stress in children.  The aim of this study is to determine if there is any relation between stress hyperglycemia and diabetes mellitus and metabolic syndrome in pediatric patients.   Materials and Methods:  The study was performed on children hospitalized in Amirkola pediatric hospital, North of Iran, bet...

conclusions according to the results of this meta-analysis, there was a high risk of nafld in women with pcos. we suggest evaluating patients with pcos regarding nafld. results we finally included seven eligible studies. according to chi-squared test, there was a significant heterogeneity (73.6%) between studies (p = 0.001). nafld prevalence was significantly higher in patients with pcos compar...

Background: Adults with polycystic ovary syndrome (PCOS) can have multiple metabolic abnormalities. However, studies in the adolescent population are still limited and these results seem to vary widely. This study was to investigate the metabolic abnormalities in adolescents with PCOS in Zanjan-Iran and potential risk factors contributed to these health risks. Materials and Methods: Anthropomet...

Metabolic Syndrome X is now a recognized medical condition. The clinical features of this disorder typically include abdominal obesity and visceral fat, fatty liver, elevated hepatic transaminases (liver enzymes), dysllpidemia, and, eventually, hypertension. Sufferers of Metabolic Syndrome have a much greater risk of developing type 2 diabetes and usually exhibit high insulin levels and insulin...

background nafld/nash is a manifestation of metabolic syndrome and is associated with obesity/overweight. not all obese/overweight individuals develop nash. gastro-esophageal reflux disease (gerd) is considered a gastrointestinal manifestation of the metabolic syndrome and is associated with obesity/overweight. again not all obese/overweight individuals develop gerd. recent data show associatio...