Staphylococcus aureus (S. aureus) has entered the spotlight as a globally pervasive drug-resistant pathogen. While historically associated exclusively with hospital-acquired infections in immunocompromised hosts, the methicillin-resistant form of S. aureus has been spreading throughout communities since the 1990s. Indeed, it has now become a common household term: MRSA. S. aureus has developed ...

Staphylococcus aureus is a gram positive, nonmotile bacterium which normally colonizes in skin and mucosa of human and animal, transmitted by direct contact or via contaminated surfaces, which causes infections like skin infections , respiratory infections and food poisoning. Methicillin is a narrow spectrum betalactam antibiotic of the penicillin class which was previously used for the treatme...

A total of 56 Staphylococcus aureus isolates incubated for 2 h in the presence or absence of oxacillin were analyzed by flow cytometry after labeling with an S. aureus-specific peptide nucleic acid (PNA) probe. Two defined ratios, the paired signal count ratio (PSCR) and the gate signal count ratio (GSCR), differentiated methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aure...

While the increasing importance of methicillin-resistant Staphylococcus aureus (MRSA) as a pathogen in health care-associated S. aureus pneumonia has been documented widely, information on the clinical and economic consequences of such infections is limited. We retrospectively identified all patients admitted to a large U.S. urban teaching hospital between January 2005 and May 2008 with pneumon...

On May 16, 1990, Division L (Nosocomial Infections) of the American Society for Microbiology (ASM) held a seminar on methicillin-resistant Staphylococcus aureus (MRSA) as part of the Society’s 90th annual meeting. The seminar was convened by Maury E. Mulligan, MD, and one of the editors (AIH). Subsequently, the speakers submitted manuscripts related to topics they presented. Because of the mark...

BACKGROUND Staphylococcus aureus, an important nosocomial pathogen, is frequently associated with infections in human. The management of the infections by it especially methicillin resistant ones is often difficult because methicillin resistant S. aureus is usually resistant to multiple antibiotics. Macrolide-lincosamide streptogramin B family of antibiotics is commonly used to treat such infec...

We investigate the in-hospital transmission dynamics of two methicillin-resistant Staphylococcus aureus (MRSA) strains: hospital-acquired methicillin resistant S. aureus (HA-MRSA) and community-acquired methicillin-resistant S. aureus (CA-MRSA). Under the assumption that patients can only be colonized with one strain of MRSA at a time, global results show that competitive exclusion occurs betwe...

Sir Methicillin resistant acquired S. aureus (MRSA) infection is an important infection in the hospitals worldwide. Nasal colonization with S. aureus especially among healthcare personnel plays as a significant role in the increasing prevalence of resistant community acquired S. aureus infections (1, 2). Colonized patients and also health personnel are the important sources of S. aureus and MRS...

BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen frequently isolated in both hospital and community environments. Methicillin-resistant Staphylococcus aureus is considered a major nosocomial pathogen that causes severe morbidity and mortality. OBJECTIVES The main objective of this study was to determine the genotypes of MRSA strains isolated from the nares...