Objective The literature on managing migraine non-responsive to pharmacological approaches and that co-occurring with depression is scanty. The comorbid condition predicts a poorer prognosis for migraine as well as depression. The present report assesses efficacy and tolerability of high frequency repetitive transcranial magnetic stimulation (rTMS) over left dorsolateral prefrontal cortex as a ...

Studies have shown fluctuations of cytokine levels in patients with migraine headaches; however, further studies are needed to verify these results. Our previous studies suggest increased levels of pro-inflammatory cytokines, such as IL-1alpha, sTNF-RI and TNF-alpha, in children with migraine headaches. In this study, we analyzed anti-inflammatory cytokines interleukin-4 (IL-4), interleukin-10 ...

Background and Purpose—Previous P–magnetic resonance spectroscopy (P-MRS) studies have shown that cerebral cortical energy metabolism is abnormal in migraine and that cortical energy reserves decrease with increasing severity and duration of aura. Migrainous infarction is a rare complication of migraine with aura, and its pathophysiology is poorly understood. We used P-MRS to determine whether ...

background: migraine is a prevalent disease which is classified into two groups of migraine with aura and without aura. eighteen percent of women and 6.5 percent of men in united states have migraine headache. migraine headache is prevalent in all age groups but it usually subsides in adults above fifty. migraine has many risk factors such as stress, light, tiredness, special foods and beverage...

Objective The aim of the present research was to compare the effectiveness and tolerability of melatonin and amitriptyline in pediatric migraine prevention. Materials & Methods In a parallel single-blinded randomized clinical trial, 5-15 yr old children with diagnosis of migraine that preventive therapy was indicated in whom and were referred to Pediatric Neurology Clinic of Shahid Sadoughi M...

Background & Aims: The aim of this study was to the compare perfectionism, aggression and coping styles in patients with migraine and tension-type headache and healthy individuals. Methods: In this casual-comparative method study, the studied sample consisted of 42 patients with tension-type headache diagnosis, 40 patients with migraine headache selected among those referred to medical centers ...

OBJECTIVE To describe the prevalence, sociodemographic profile, and the burden of migraine in the United States in 1999 and to compare results with the original American Migraine Study, a 1989 population-based study employing identical methods. METHODS A validated, self-administered questionnaire was mailed to a sample of 20 000 households in the United States. Each household member with seve...

Migraine without aura is frequently reported in female patients with irritable bowel syndrome (IBS), but knowledge about the relationship between these two conditions is still lacking. This study was aimed to explore the particularities of migraine without aura in young female patients with IBS in order to establish a possible link between them. From a cohort of young female patients hospitaliz...

Abstract Background Migraine is a common, chronic, multifactorial neurovascular disorder. It may result in hypoperfusion of other areas than the brain, as eye. lead to change retinal nerve fiber layers (RNFL) thickness and axonal loss even up severe damage eye structures, including retina with frequent headache attacks. This study aimed quantify RNFL which gives good idea about condition axons ...