background: the prevalence of food allergy is different in different parts of the world. identification of the most common food allergens is a priority in any population to provide effective preventive and curative measures.   objective: the aim of this study was to determine the most common food allergens in iranian children.   methods: one hundred and ninety children with skin, respiratory or...

Cow's milk protein allergy (CMPA) represents one of the leading causes food in infants and young children. The immune reaction mainly due to casein β-lactoglobulin protein. Many systems are affected specially GIT,respiratory system skin.

An ELISA was applied to measure IgG sub-class antibodies to cow's milk beta-lactoglobulin (BLG), alpha-lactalbumin (ALA) and alpha-casein (AC) and to hen's egg ovalbumin (OA) in the sera of nineteen adult patients with milk intolerance causing either asthma, eczema or both. Results were compared with those of forty blood donors and twenty adult patients with either asthma or eczema due to inhal...

BACKGROUND Cow's milk protein allergy is the most common cause of food allergy. The challenge test, either open or doubled-blind with a placebo control, is regarded as the criterion standard. Endoscopy and histologic findings are considered a method that can aid in the diagnosis of this entity. AIMS The aim of this study was to describe the histopathologic findings in children suspected of co...

Although some animal models of food allergy in have already have been described, none of them uses the allergen in the animals' diet. This work describes the comparison between two developed models of food allergy in BALB/c mice, based in the administration of the allergen in the diet or by intragastric way. The experiment last for 28 days and the animals had been sensitized by means of subcuta...

The purpose of this editorial is to highlight the recent ratification as WAO Position Papers of 2 important documents published in the World Allergy Organization Journal (WAO Journal). The “World Allergy Organization (WAO) Guidelines on the Diagnosis and Rationale against Cow’s Milk Allergy (DRACMA) Guidelines,” ratified as a WAO Position Paper by the WAO House of Delegates, March 21, 2011, inv...

PURPOSE OF REVIEW To identify and discuss studies on the molecular diagnosis of cow's milk allergy (CMA) with a view to update allergists since a general review of the methodology in 2006. RECENT FINDINGS Seven basic research studies reporting the use of component-resolved diagnostics in CMA were found. All studies were on children positively reacting to a formal challenge with cow's milk. Si...

Epicutaneous immunotherapy is a developing technique, aiming at desensitizing patients with food allergy with less risks that oral ingestion or injection could generate. Several clinical trials have been performed and are currently running, in milk and peanut allergy, assessing the safety of the technique and its efficacy. Preclinical models indicate a major role in the mechanisms of desensitiz...

Milk elimination diets are frequently adopted in the treatment of atopic dermatitis, although the real prevalence of clinically relevant food allergy remains unclear and reports from different authors are often in disagreement. We investigated the percentage of children allergic to cow's milk compared with the rate of milk exclusion diets in a group of patients with atopic dermatitis. We enroll...