Rapid antifungal susceptibility testing for the antifungal agent caspofungin can be performed using flow cytometry (FC). An FC procedure using acridine orange provided minimum inhibitory concentration (MIC) results within 7 to 9 h which were compared with results obtained using the NCCLS M27-A2 protocol. To evaluate the consistency of this method, susceptibility testing using caspofungin was pe...

Studies on the antioxidant and antimicrobial activities of Mitragyna speciosa leaf extracts are lacking. In this study the antioxidant properties of water, methanolic and alkaloid M. speciosa leaf extracts were evaluated using the DPPH (2,2-diphenyl-1- picrylhydrazyl) radical scavenging method. The amount of total phenolics and flavanoid contents were also estimated. The DPPH IC(50) values of t...

In the last decade the number of Acinetobacter baumannii and Pseudomonas aeruginosa isolates showing extended drug resistance and pandrug resistance has steadily increased, thereby limiting or eliminating the antibiotics that can be used to treat infections by these micro-organisms. In addition, few antibiotics have been launched in the last decade. The objective of this study was to investigat...

in our study, bioactivity of essential oil extracted from ginger (zingiber officinaleroscoe.) that belongs to family zingiberaceae was analyzed. ginger rhizome oil was found to be effective against a range of bio-deteriogens. the minimum inhibitory concentration (mic) value was determined by poisoned food technique and volatile activity assay. the study demonstrates that essential oil had a wid...

Antimicrobial efficacy of flavonoids (free and bound) and crude alkaloids of Lantana camara L. was determined by disc diffusion assay against three bacteria (Escherichia coli, Proteus mirabilis, and Staphylococcus aureus) and two fungi (Candida albicans and Trichophyton mentagrophytes). Minimum inhibitory concentration, minimum bactericidal/fungicidal concentration and total activity were also ...

background periodontitis is a major problem that affects a large number of patients in the society. various treatment alternatives have been proposed to control this pathologic condition. streptococcus sanguis is one of the countless pathogens involved in periodontitis. objectives the current study aimed to assess the efficacy of pineapple extract per se and in synergy with vancomycin on the gr...

The rate of development of antibiotic resistance by microorganisms is pretty high compared to the discovery of new antibiotics. Therefore new formulations have come up in order to avoid resistance, either through increasing the availability or penetration of the already existing drugs(Arias, 2013). Delivery of antimicrobials or other compounds in the form of liposome is gaining more attention (...