PURPOSE The genomic instability in colon cancer can be divided into at least two major types, microsatellite instability (MSI) or chromosomal instability (CIN). Although initially felt to be mutually exclusive, recent evidence suggests that there may be overlap between the two. The aim of this study was to identify chromosomal alterations at high resolution in sporadic colon cancers with high-l...

Increasing plant species diversity has been proposed as a means for enhancing annual pasture productivity and decreasing seasonal variability of pasture production facing more frequent drought scenarios due to climate change. Few studies have examined how botanical complexity of sown swards affects cow performance. A 2-year experiment was conducted to determine how sward botanical complexity, f...

In this paper, we propose a new detector of which the basis is on the median-shift sign. We call it the median-shift sign (MSS) detector, which is a generalization of the classical (standard) sign detector. First, we consider the asymptotic optimum median shift (MS) values and their characteristics. Next we consider the asymptotic relative efficiency (ARE) of the MSS detectors.

Modern research has engendered frameworks, such as the management support system (MSS), that are designed to provide comprehensive and integrated support for the decision making process. While one recent study has empirically measured the effects of these frameworks on decision making, there have been few, if any, corroborating or deprecating investigations. This article offers further empirica...

The Marinesco-Sjögren syndrome (MSS) (MIM 248800) is an autosomal recessive condition characterised by cataracts, ataxia, and growth and mental retardation. Chronic myopathy is a common feature. Peripheral neuropathy and acute rhabdomyolysis have been described occasionally in MSS. To date, no gene for it has been localised. Congenital cataracts-facial dysmorphism-neuropathy syndrome (CCFDN) (M...

Marinesco-Sjögren syndrome (MSS) is a rare autosomal recessively inherited disorder with mental retardation (MR). Recently, mutations in the SIL1 gene, encoding a co-chaperone which regulates the chaperone HSPA5, were identified as a major cause of MSS. We here examined the pathophysiological significance of SIL1 mutations in abnormal corticogenesis of MSS. SIL1-silencing caused neuronal migrat...

We measured thresholds for comparing the separation between lines, using either the method of constant stimuli (MCS) or the method of single stimuli (MSS). In the MCS an explicit standard is presented on each trial, whereas in the MSS the standard is the mean of the set. The thresholds for the MSS procedure were nearly identical to those with the MCS procedure, whether or not feedback was used....

Rhythms occur both in neuronal activity and in behavior. Behavioral rhythms abound at frequencies at or below 10 Hz. Neuronal rhythms cover a very wide frequency range, and the phase of neuronal low-frequency rhythms often rhythmically modulates the strength of higher-frequency rhythms, particularly of gamma-band synchronization (GBS). Here, we study stimulus-induced GBS in awake monkey areas V...

Data broadcasting has been commonly deployed in many emerging mobile applications such as intelligent transportation systems and locationbased services because it is a scalable approach to disseminating information from the mobile support station (MSS) to a large population of mobile hosts (MHs). To provide timely data access and better data availability, MHs can store data items broadcast by t...