Diffuse optical tomography (DOT) is an emerging technology for improving the spatial resolution and spatial specificity of conventional multi-channel near-infrared spectroscopy (NIRS) by the use of high-density measurements and an image reconstruction algorithm. We recently proposed a hierarchical Bayesian DOT algorithm that allows for accurate simultaneous reconstruction of scalp and cortical ...

OBJECTIVES Dependence on prescription opioids (PO) is a growing problem. Although most research with buprenorphine has focused on heroin-dependent populations, we hypothesize that individuals dependent on PO display characteristics that may predict different outcomes in treatment, particularly in short-term taper procedures in which comorbidities such as pain conditions may complicate taper. ...

We measured the perceived direction of one motion component as a function of the contrast and speed of a second component for three pattern classes: plaids with two different spatial frequency components, multi-aperture patterns, and contrast-modulated (CM) patterns. The components were moving at +/- 63.4 or +/- 71.6 deg to the vertical, angles where motion transparency always occurred under ou...

OBJECTIVES An ongoing prospective study to investigate failing metal-on-metal hip prostheses was commenced at our centre in 2008. We report on the results of the analysis of the first consecutive 126 failed mated total hip prostheses from a single manufacturer. METHODS Analysis was carried out using highly accurate coordinate measuring to calculate volumetric and linear rates of the articular...

A modular femoral head-neck junction has practical advantages in total hip replacement. Taper fretting and corrosion have so far been an infrequent cause of revision. The role of design and manufacturing variables continues to be debated. Over the past decade several changes in technology and clinical practice might result in an increase in clinically significant taper fretting and corrosion. T...

Recently, a large set of electroencephalography (EEG) data is being generated by several high-quality labs worldwide and is free to be used by all researchers in the world. On the other hand, many neuroscience researchers need these data to study different neural disorders for better diagnosis and evaluating the treatment. However, some format adaptation and pre-processing are necessary before ...

We propose a novel spectral filter optimization algorithm for the single trial ElectroEncephaloGraphy (EEG) classification problem. The algorithm is designed to improve the classification accuracy of Common Spatial Pattern (CSP) based classifiers. The algorithm is based on a simple statistical criterion, and allows the user to incorporate any prior information one has about the spectrum of the ...