Objective: The current research was based on developing CS-PLGA nanoparticles (NPs) drug delivery system (DDS) for improving the bio-availability of metformin HCl, an anti-diabetic drug. Methods: Nanoprecipitation method utilized to prepare HCl-loaded NPs DDS. were validated using analytical and characterization also done. These polymers release in a controlled manner. Results: correlation coef...

In this study, eugenol-loaded mPEG-PCL nanoparticles were used to improve the anti-bacterial properties of eugenol in an attempt eliminate resistant bacteria. The copolymer was prepared by ring-opening polymerization [Formula: see text]-caprolactone monomer vicinity a dry mPEG and tin (II) octoate catalyst. Polymeric through nanoprecipitation procedure. particle size zeta potential mPEG-PCL/eug...

Different methods which could be used to produce colloidal dispersions of polyaniline (PANI) nano-objects without templates are described. While the non-deterministic, different (nanospheres, nanofibers, nanobelts, nanorice, nanotubes, nanorods, nanodisks, etc.) can produced. Those most are: (i) solution polymerization with steric stabilizers (SPS) nanospheres, (ii) interfacial (IP) nanofibers ...

The recent interest in the application of organic semiconductor colloids to photocatalytic hydrogen evolution has sparked need for an assessment current state this research field. Here, we showcase how lessons learned from photovoltaics (OPV) can be applied new applications generation solar fuels, such as evolution. Photovoltaics generated nanoparticles (NPs) started with a power conversion eff...

Doxorubicin (DOX)-loaded polymer nanoparticles based on poly(ethylene glycol)-poly(ε-caprolactone) copolymers with a complex macromolecular topology are proposed to tackle the matrix metalloproteinase (MMP)-rich tumor environment. Linear, 4-arm comb-like and brush block were synthesized through combination of ring opening polymerization atom transfer radical polymerization, in order control mol...

The use of self-assembled nanoparticles for drug delivery has received significant attention in recent years. However, the dynamic nature polymeric systems means there is a need to develop greater understanding inherent stability these systems. In particular, if materials remain as discrete nanoparticles, or exchange material between particles critical. Herein, we labelled pH-responsive with fl...