نتایج جستجو برای: nephroprotective effects
تعداد نتایج: 1544573 فیلتر نتایج به سال:
Methotrexate is an effective anticancer and immunosuppressive agent. However, nephrotoxicity is one of the complications of its use. On the other hand, curcumin, a naturally occurring polyphenolic compound, is reported to have antioxidant and anti-inflammatory properties. Those two properties are likely to prevent methotrexate-induced nephrotoxicity. The aim of this study is to evaluate the pos...
Recently, among general practitioners – family doctors, therapists, specialists, there is a growing interest to the use of phytotherapy for prevention and treatment various pathologies. One classic examples medicinal plant with long history human Spanish Artichoke. The objective: analyze results pharmacokinetic pharmacodynamic studies standardized artichoke extract (SAE). Materials methods. rev...
Ischemic acute kidney injury (iAKI) in diabetes mellitus is associated with a rapid deterioration of kidney function, more than in nondiabetic subjects. TVP1022, a non-MAO inhibitor S-isomer of rasagiline, possesses antioxidative and antiapoptotic activities. The current study examines the effects of TVP1022 and tempol on iAKI in diabetic rats. Diabetes was induced by streptozotocin. iAKI was i...
Methylglyoxal (MGO), an active metabolite of glucose, has been reported to induce vascular cell apoptosis in diabetic complication. Polydatin (PD), a small natural compound from Polygonum cuspidatum, has a number of biological functions, such as antioxidative, anti-inflammatory, and nephroprotective properties. However, the protective effects of PD on MGO-induced apoptosis in endothelial cells ...
BACKGROUND Experimentally, erythropoietin (EPO) has nephroprotective as well as immunomodulatory properties when administered after ischemic renal injury. We tested the hypothesis that different doses of recombinant human EPO administered to patients after cardiac surgery would minimize kidney lesions and the systemic inflammatory response, thereby decreasing acute kidney injury (AKI) incidence...
this study examined the effects of collaborative strategic reading and direct instruction in persuasion on iranian high school students persuasive writing and attitudes. students in three intact classes were assigned to one of three treatment conditions: collaborative strategic reading and direct instruction in persuasion or direct instruction in persuasion or a control group. treatment effects...
Urtica dioica L. is widely used as an anti‑inflammatory, antioxidant, antimicrobial, hypocholesterolemic, antiulcer, anti‑colitis, anticancer, hypotensive, immunomodulatory, and hepatoprotective agent. In the present study, the antidiabetic and nephroprotective potentials of U. dioica ethanolic extract was investigated against streptozotocin (STZ) induced diabetic mice. Male mice were divided i...
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