introduction: ischaemic-reperfusion nerve injury has been suggested as the mechanism for post-tourniquet limb paralysis. as dexamethasone (dex) has been shown to prevent ischaemic-reperfusion process in some tissues, we tested the hypothesis that this drug would reduce tourniquet induced nerve injury. methods: 36 male wistar rats (200-250 gr) were chosen and divided randomly into 6 equal groups...

BACKGROUND Large amounts of local anaesthetics (LA) are used during psoas compartment block (PCB), especially if combined with sciatic nerve block. Data regarding early pharmacokinetics of ropivacaine for PCB are lacking, notably when a vasoconstrictive agent has not been added. METHODS PCB was established in 11 patients using 150 mg ropivacaine without epinephrine. Free and total arterial pl...

Comprehensive electrophysiological studies were performed on 13 patients with arsenic neuropathy. The most prominent finding was a marked abnormality in sensory nerve conduction in the presence of moderate abnormalities in motor nerve conduction. The motor nerve conduction studies and needle EMG were typical of those seen in axonal degeneration which was confirmed by sural nerve biopsy.

Recordings of single human peroneal C-fibres and rat saphenous C-fibres confirm two different patterns of conduction at branching points. In general, an action potential (AP) arising from one terminal branch may be propagated not only centrally, but also antidromically into the other branches of the terminal arborisation. If a stimulus activates several converging branches of one unit, at each ...

Objective: The aim of present study was to evaluate the effects of oral administration of gallic acid (GA) for 21 days alone and in combination with exercise on nerve conduction velocity and sensory and motor functions in rats with sciatic nerve crush. Materials and Methods: Seventy adult male Wistar rats (250-300 g) were divided randomly into 7 groups with 10 in each: 1) Control (Cont), 2) Cru...

OBJECTIVE The objective of this study was to test whether monotone worsening of nerve function, attributable to diabetes, can be demonstrated before criteria for diabetic sensorimotor polyneuropathy (DSPN) have been met. Which nerve tests are best? RESEARCH DESIGN AND METHODS From a prevalence cohort of 504 individuals in the Rochester Diabetic Neuropathy study (RDNS), we identified 238 indiv...

BACKGROUND Tibial mononeuropathy due to compression by a synovial cyst is uncommon with fewer than 10 cases reported in the literature. METHOD Case Study. RESULTS Tibial motor mononeuropathy with focal conduction block between the popliteal fossa and ankle was identified by electrophysiological testing. Magnetic resonance imaging and surgical exploration identified a synovial cyst compressi...

Background: Few reports represent palmar cutaneous nerve neuropathy in the wrist due to a ganglion cyst. Case Presentation: A 25-year-old female was presented with a mass at volar side of the wrist and hypoesthesia at the base of thenar eminence. At ulrasonographic examination, a simple cyst was detected. Sensory response of palmar cutaneous branch of median nerve was absent at the affec...

We have studied conduction anaesthesia of the median and ulnar nerves at the axilla using mixed nerve action potentials (MNAP) as a guide to needle position in three volunteers. The median and ulnar nerves were stimulated distally at the wrist using surface electrodes and MNAP were detected proximally in the axilla using an insulated needle electrode. The increase in amplitude of MNAP to maximu...

Monosynaptic excitatory postsynaptic potentials (EPSPs) evoked in rat spinal motoneurons by stimulation of a muscle nerve are enhanced during the first few days after section of the muscle nerve before subsiding to subnormal levels. We have examined whether this biphasic alteration results from changes of different factors involved in the regulation of central synaptic function. We chronically ...