normal 0 false false false en-us x-none ar-sa in this case report, we present a 30‑year-old man who developed pityriasis rubra pilaris (prp) following exposure to dolomite. the diagnosis of prp was confirmed histologically and the patient was successfully treated with acitretin and cyclosporine.

A global understanding of the actions of the nuclear hormone 1α,25-dihydroxyvitamin D(3) (1α,25(OH)(2)D(3)) and its vitamin D receptor (VDR) requires a genome-wide analysis of VDR binding sites. In THP-1 human monocytic leukemia cells we identified by ChIP-seq 2340 VDR binding locations, of which 1171 and 520 occurred uniquely with and without 1α,25(OH)(2)D(3) treatment, respectively, while 649...

The postcranial system is composed of the axial and appendicular skeletons. The axial skeleton, which consists of serially repeating segments commonly known as vertebrae, protects and provides leverage for movement of the body. Across the vertebral column, much numerical and morphological diversity can be observed, which is associated with axial regionalization. The present article discusses th...

Consider a Markov process with countably many states. In order to find a one-state occupation time distribution, we use a combination of Fourier and Laplace transforms in the way that allows for the inversion of the Fourier transform. We derive a closed-form expression for the occupation time distribution in the case of a simple continuous time random walk on Z and represent the one state occup...

Transposable elements, or transposons, are selfish genetic elements that possess the ability to mobilize within a genome, potentially causing serious damage. They can accomplish this through several well-understood mechanisms. Most move via an RNA intermediate (class I: retrotransposons), whereas others colonize new locations through the direct transfer of transposon DNA (class II: DNA transpos...

The past 5 years have seen increasing calls to reexamine our assessment and intervention practices to ensure that they reflect the profession's basic focus on occupation. Although a number of noteworthy efforts in this direction have been presented for adult practice areas, implementation of occupation-centered assessment in pediatric has been hampered by the lack of a consistent framework to g...

The heterogeneous pathology of tauopathies and the differential susceptibility of different neuronal types to WT (wild-type) and mutant tau suggest that phosphorylation at particular sites rather than hyperphosphorylation mediates toxicity or dysfunction in a cell-type-specific manner. Pan-neuronal accumulation of tau in the Drosophila CNS (central nervous system) specifically affected the MBs ...

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