BACKGROUND Adherence to highly active antiretroviral therapy (HAART) medication is the greatest patient-enabled predictor of treatment success and mortality for those who have access to drugs. We systematically reviewed the literature to determine patient-reported barriers and facilitators to adhering to antiretroviral therapy. METHODS AND FINDINGS We examined both developed and developing na...

The family has not been exempt from the multiple and rapidly occurring changes in the world today, particularly in market economies. The number of marriages has declined, age at first marriage has risen, the number of divorces has risen sharply, the fertility rate has declined, and the division of labor within families has changed, not always in ways that might be expected. This paper subjects ...

The unstable flow with rotating-stall-like (RS) effects in a rotor-cascade of an axial compressor was numerically investigated. The RS was captured with the reduction in mass flow rate and increasing of exit static pressure with respect to design operating condition of the single rotor. The oscillatory velocity traces during the stall propagation showed that the RS vortices repeat periodically,...

The unstable flow with rotating-stall-like (RS) effects in a rotor-cascade of an axialcompressor was numerically investigated. The RS was captured with the reduction in mass flow rateand increasing of exit static pressure with respect to design operating condition of the single rotor.The oscillatory velocity traces during the stall propagation showed that the RS vortices repeatperiodically, and...

Research that helps people change their behavior has the potential to improve quality of lives, but it is too often approached in a way divorces from who need enact it. In this paper, we propose personality-informed approach classifying behavior-change problems and designing interventions address them. particular, argue will be most effective when they target appropriate psychological process g...

Concerns of pride, dignity and the desire to “keep hope” about future options often lead individuals and groups to walk away from reasonable offers, try to shift blame for failure onto others or take refuge in political utopias, leading to impasses and conflicts. Examples include trials, divorces, strikes, the scapegoating of minorities for economic hardships, and war. A key and puzzling aspect...

pulmonary langerhans cell histiocytosis (plch) is a rare idiopathic disorder that primarily affects young adult cigarette smokers. affected patients often present with cough and dyspnea and about 20% of patients present with or later develop pneumothorax. it is striking that more than 90% of patients are smokers. we report a very unusual case of plch in a 20-year- old male patient with no smoki...

A new series of imidazo[2,1-b]thiazole analogs containing a methyl sulfonyl COX-2 pharmacophore was synthesized and evaluated for their COX-2 inhibitory activity. According to in-vitro COX-1/COX-2 inhibition data, all compounds (6a-g) were selective inhibitors of COX-2 isoenzyme with IC50 values in the highly potent 0.08-0.16 mM range. These results indicated that both potency and selectivity o...