INTRODUCTION Early-onset dementia (EOD) is defined as dementia with onset before the age of 65 years. EOD is increasingly recognised as an important clinical and social problem with devastating consequences for patients and caregivers. OBJECTIVE Determine the annual crude incidence rate and the specific incidence rates by sex and age in patients with EOD, and the standardised rate using the l...

Several linkage studies across multiple population groups provide convergent support for a susceptibility locus for schizophrenia--and, more recently, for bipolar disorder--on chromosome 6q13-q26. We genotyped 192 European-ancestry and African American (AA) pedigrees with schizophrenia from samples that previously showed linkage evidence to 6q13-q26, focusing on the MOXD1-STX7-TRARs gene cluste...

Background: Anti-neutrophil cytoplasmic antibody (ANCA)associated vasculitis (AAV) comprises microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic GPA (EGPA). Myeloperoxidase (MPO) and proteinase 3 (PR3) are the main antigens for ANCA. AAV is a common multisystem autoimmune disease and most of the studies on AAV have been conducted in Western countries. Nowaday...

This historical essay outlines early ideas and clinical accounts of hysteria. It reproduces verbatim parts of a remarkable text of Thomas Sydenham. This provides the most detailed description of hysterical symptoms, contemporary treatment and particularly Sydenham’s opinions about the nature of the disorder. His portrayal is compared to later and modern concepts and classification. © 2016 S. Ka...

this paper has examined the phenomenon of convergence of per capita out put levels across the ic countries for the 1960-1998 periods. three concepts of convergence, i.e., sigma beta and relative beta, have been used. the estimated beta values reveals only a very weak convergence (?=.0014) across ic for 1960-1998 period. but when a more homogeneous group of countries were selected, the results s...

Background: Anti-neutrophil cytoplasmic antibody (ANCA)associated vasculitis (AAV) comprises microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic GPA (EGPA). Myeloperoxidase (MPO) and proteinase 3 (PR3) are the main antigens for ANCA. AAV is a common multisystem autoimmune disease and most of the studies on AAV have been conducted in Western countries. Nowaday...