Purposes: Propranolol HCl is a beta blocker commonly used worldwide; however, it shows a low bioavailability due to its extensive first-pass metabolism. To solve this problem, a novel drug delivery system such as buccoadhesive system might be helpful. The aim of the present investigation is to prepare the buccoadhesive tablet of propranolol HCl using different mucoadhesive polymers. Method: Buc...

meloxicam is a poorly water soluble non steroidal anti-inflammatory drug and antipyretic agent. the aim of the present work was to investigate the effect of different types of carriers on in vitro dissolution of meloxicam. meloxicam solid dispersions were prepared by physical mixing, co-grinding and solvent evaporation methods with polyethylene glycol (peg) 6000. the effect of solubilization by...

Priming fresh and naturally aged canola seeds with different substances observing the seed germination properties are involved in this work. Fresh of cv. “süzer” were treated distilled water, -0.8 MPa polyethylene glycol (PEG) 6000 50 mM thiamine for 8 hours. Storage showed loss capacity compared to seeds. Present findings indicate that priming can improve speed both canola. Germination percent...

A sensitive RIA for benzoylecgonine in body fluids is described. The label is radioiodinated p-hydroxybenzoylecgonine. The antiserum from an Emit-dau cocaine metabolite kit (Syva) is used at a 1:600 dilution. The standards are benzoylecgonine in buffer. PEG-6000 is used to separate the bound and free fractions. Cocaine, ecgonine, and methylecgonine have cross-reactivities of 2%, 1%, and 0.1%, r...

Abstract In the present study, mutual diffusivity D 11 in binary mixtures of water with technical polydisperse poly(ethylene) glycol (PEG) blends molar masses (1000, 4000, or 6000) g⋅mol −1 as well a purified monodisperse PEG homolog polymerization number 21 and mass 943 was investigated by heterodyne dynamic light scattering (DLS) function temperature and/or concentration. The measured for 100...

Meloxicam is a poorly water soluble non steroidal anti-inflammatory drug and antipyretic agent. The aim of the present work was to investigate the effect of different types of carriers on in vitro dissolution of meloxicam. Meloxicam solid dispersions were prepared by physical mixing, co-grinding and solvent evaporation methods with polyethylene glycol (PEG) 6000. The effect of solubilization by...

(1) Background: The surveillance of SARS-CoV-2 RNA in urban wastewaters allows one to monitor the presence virus a population, including asymptomatic and symptomatic individuals, capturing real circulation this pathogen. aim study was evaluate performance different pre-analytical analytical methods for identifying untreated municipal samples by conducting an inter-laboratory proficiency test. (...

Abstract: Tomato is a crop sensitive to water deficit and the responses of seeds germination under these conditions involve biochemical, physiological, molecular processes. The aim this study was evaluate physical, biochemical changes in tomato osmoprimed with selenium (Se) subjected during germination. LA 4050 3475 accessions were PEG 6000 solution (-1.0 MPa) plus Na2SeO4 (12.5 μM) or only for...

Phenylethanolamine N-methyltransferase, PNMT, utilizes the methylating cofactor S-adenosyl-L-methionine to catalyse the synthesis of adrenaline. Human PNMT has been crystallized in complex with an inhibitor and the cofactor product S-adenosyl-L-homocysteine using the hanging-drop technique with PEG 6000 and lithium chloride as precipitant. A critical requirement for crystallization was a high e...