Ten milliliters of whole blood were withdrawn from 30 patients with one or more chronic periapical lesions measuring 10 x 10 mm or larger on radiographs taken before root canal therapy. Also, blood was withdrawn from 32 patients with known allergies (positive controls) and 30 individuals with no known allergies and no periapical or periodontal lesions (negative controls). The sera of the three ...

OBJECTIVES In an attempt to elucidate if inducible nitric oxide expression (iNOS) is correlated with the level of inflammation in periapical cysts with accuracy, the goal of this study was to evaluate the expression of iNOS in these ones. METHODS 30 cases were included in this study being iNOS evaluated by means of immunohistochemistry. Statistical analysis was performed by Kruskal-Wallis non...

This article presents non-surgical resolution of an extensive periapical lesion of endodontic origin associated with the maxillary left lateral incisor. Clinical examination revealed an asymptomatic bony hard swelling confined to the palate, while radiographic analysis showed a lesion measuring 22 mm in diameter and nearly 389 mm(2) in area. Through apical patency, 4 ml of intracanal exudate wa...

The widespread use of oral implants in recent years has resulted in various types of complications. One of those complications is the periapical implant lesion. Different factors have been proposed to play a role in the development and emergence of a periapical implant lesion. To date, there is no consensus on the etiology and therefore periapical lesions around dental implants are considered t...

BACKGROUND Cutaneous odontogenic fistulas or sinus tracts are frequently misdiagnosed and incorrectly treated, leading to unnecessary procedures and patient suffering. An understanding of the draining of cutaneous sinus tracts will lead to more appropriate treatment. Most cases respond to conservative, nonsurgical root canal therapy. Our objective is to report 2 cases of cutaneous sinus tract s...

INTRODUCTION ST2 is a member of the interleukin (IL)-1 receptor family, and IL-33 is its natural ligand. ST2 signaling promotes Th2 immune response in allergy, autoimmunity, and chronic inflammatory disorders, but its role in the pathogenesis of periapical lesions is unknown. The purpose of this study was to investigate whether ST2 gene deletion affects the development of experimentally induced...

Traumatic injuries commonly affect the anterior teeth leading to slow death of the pulp. This may give rise to a periapical or radicular cyst which results from the proliferation of cell rests of Malassez following pulpal necrosis of a nonvital tooth. This condition is usually asymptomatic but can result in a slow-growth tumefaction in the affected region. On radiography the lesion can be seen ...

In teeth with periapical lesions and defective root canal seals non-surgical retreatment is usually preferred. Sometimes, however, such treatment may not be feasible and periapical surgery must be performed. The present study investigated a technique of retrograde root canal treatment as an alternative to the more conventional types of surgical procedure. The material consisted of 35 teeth whos...

A customized acrylic-resin template with gutta percha markers was fabricated for a human cadaver mandible. Twelve measurements were made between gutta percha markers and between the markers and known mandibular anatomic locations. Periapical, panoramic, and computerized tomographic radiographs were taken of the mandible and stent. Similar readings were recorded from the radiographs. The average...