In this work we propose a novel method for individualized treatment selection when there are correlated multiple responses. For the K (K≥2) scenario, compare quantities that suitable indexes based on outcome variables each conditional patient-specific scores constructed from collected covariate measurements. Our covers any number of treatments and variables, it can be applied broad set models. ...

BACKGROUND The present approach to cancer treatment is often referred to as "trial and error" or "one size fits all." This practice is inefficient and frequently results in inappropriate therapy and treatment-related toxicity. In contrast, personalized treatment has the potential to increase efficacy and decrease toxicity. CONTENT We reviewed the literature relevant to prognostic, predictive,...

Pancreatic cancer, among which pancreatic ductal adenocarcinoma (PDAC) is the most common type, has a nearly identical incidence to mortality rate. Difficulties in early detection, diagnosis, and treatment are primarily responsible, all of further complicated by molecular biology etiology disease. To succeed improving options survival rates, deeper understanding cancer pathogenesis, as well pat...

The purpose of this article is to provide a framework for understanding the principles personalized and precision medicine. Since advent human genome project in 1990, approach accurate medicine has been changed. This turns practice from “one size fits all” paradigm into one that tailors patient identification, diagnosis treatment. Personalized disputed vision future two decades. A humanized wil...

This study investigated the effects of personalized instruction on the achievement and attitudes of Taiwanese students on two-step mathematics word problems. A total of 136 fourth-graders in a Taiwanese public school participated in the study. Subjects initially completed a Student Survey on which they chose their favorite foods, sports, stores, classmates, and other selections. The most popula...

No single therapy benefits the majority of patients in the practice of oncology as responses differ even among patients with similar tumor types. The variety of response to therapy witnessed while treating our patients supports the concept of personalized medicine using patients' genomic and biologic information and their clinical characteristics to make informed decisions about their treatment...

Sequencing, genotyping, and large-scale phenotyping are currently available for a number of important patient cohorts and will soon be available as a result of routine medical practice. These molecular data, in conjunction with electronic medical records and rich, on-line resources, are setting the stage for truly personalized medicine. Personalized medicine promises to yield better diseas...

Experienced physicians have always used personalized therapy in clinical routine, long before the term personalized medicine was introduced. Optimal patient care is based on careful selection of patients who need treatment, and of therapeutic regimens that are likely to be effective and well tolerated. The clinical management of patients suffering from chronic hepatitis C virus (HCV) infection ...

Catamenial epilepsy refers to a seizure pattern that coincides with the menstrual period. Patients catamenial often leads intractable and may have an adverse impact on quality of life. Several medications are therapeutic options, however, there is uncertainty regarding best treatment, these fail control seizure. This makes categorized as pharmaco-resistant epilepsy. paper reported case perimens...