PURPOSE To study the feasibility/toxicity of urethral stenting with the Memokath® 028SW stent in patients undergoing prostate implant (PI) for prostate adenocarcinoma. MATERIAL AND METHODS An Investigational Device Exemption from the Food and Drug Administration (FDA) and institutional review board (IRB) approval were obtained. Twenty patients enrolled. Baseline American Urological Associatio...

The relationship between adherence, antiretroviral regimen, and viral load (VL) suppression was assessed through a 1 year prospective follow-up study among 1142 HIV-infected patient. Patients on antiretroviral therapy who attended to the pharmacy during a 6-month period were considered eligible. Those included in the final analysis were patients who had been taking the same antiretroviral thera...

BACKGROUND AND PURPOSE We tested the hypothesis that activation of phosphatidylinositol (PI) 3-kinase is involved in dilator responses of the basilar artery to acetylcholine in vivo. METHODS Responses of the basilar artery were measured by the cranial window technique in anesthetized rats. To examine the role of PI 3-kinase in acetylcholine-induced calcium signaling, we measured intracellular...

BACKGROUND AATD is one of the most common inherited disorders in the World. However, it is generally accepted that AATD in North African populations is not a risk factor for lung and/or liver disease, based on a number of small studies. We therefore planned a screening study for detection of AATD in patients with OLD in a cohort of patients from Kairouan in central Tunisia. METHODS One hundre...

Results A cohort of 204 patients was studied. Age 51 +/9 years; 156 (76,5%) were male; Logistic Euroscore (LE) of 5.1 +/8.4, LVEF 58 +/11. Surgery was 86 (42.2%) CABG, 79 (38.7%) valvular, 16 (7.8%) combined surgery and 23 (11.3%) others. 28 (13.7%) were self-employed. 15 of them already had a PI at the time of surgery. Patients with PI presented a LE of 6.7+/3.9 Vs. 11+/5 (p = 0.006); age 53+/...

We measure the branching fractions and $CP$ asymmetries for decays $B^{0}\to \bar{D}^{0}\pi^{0}$ $B^{+}\to \bar{D}^{0}\pi^{+}$, using a data sample of $772\times 10^{6}$ $B\bar{B}$ pairs collected at $\Upsilon(4S)$ resonance with Belle detector KEKB $e^{+}e^{-}$ collider. The obtained direct are $\mathcal{B}(B^{0}\to \bar{D}^{0}\pi^{0}) = [2.70 \pm 0.06~ \text{(stat.)} 0.10~ \text{(syst.)}] \ti...

Supplementary materials to the main paper. 1. Proofs Proof of Proposition 4 Proof. We have E[Sk] = ∑ i∈V Ezi [1{zi=k∧yi=k}] = ∑ i∈V pi(k)1{yi=k}. Likewise we have E[Tk] = ∑ i∈V Ezi [1{zi=k∨yi=k}] = ∑ i∈V Ezi [1{zi=k} + 1{yi=k} − 1{zi=k∧yi=k}] = ∑ i∈V (pi(k) + 1{yi=k} − pi(k) 1{yi=k}) = ∑ i∈V (1{yi=k} + pi(k) 1{yi 6=k}). Proof of Proposition 5 Proof. In (5) the first central moment 〈Tk〉 is alway...

We studied effects of increasing the length of porcine trachealis muscle on 5.5 microM carbachol (CCh)-evoked phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] synthesis and other parameters of phosphatidylinositol (PI) turnover. PI(4,5)P2 resynthesis rates in muscle held at 1.0 optimal length (L(o)), measured over the first 6 min of CCh stimulation, were 140 +/- 12 and 227 +/- 14% of values fo...