Abstract Computing small kernels for the hitting set problem is a well-studied computational where we are given hypergraph with n vertices and m hyperedges, each of size d some constant , parameter k . The task to compute new hypergraph, called kernel whose polynomial respect which has size- if, only original one. State-of-the-art algorithms $$k^d$$ <mml:math xmlns:mml="http://www.w3.org/1998/M...

Biocompatible and long-circulating (maghemite/poly(d,l-lactide-co-glycolide))/chitosan (core/shell)/shell nanoparticles with promising theranostic applications (biomedical imaging hyperthermia) against cancer.

Co-crystallization of polymers with different configurations/tacticities provides access to materials with enhanced performance. The stereocomplexation of isotactic poly(L-lactide) and poly(D-lactide) has led to improved properties compared with each homochiral material. Herein, we report the preparation of stereocomplex micelles from a mixture of poly(L-lactide)-b-poly(acrylic acid) and poly(D...

The enzymatic degradation of fluorescein conjugates of poly-L-lysine, poly-D-lysine, and exhaustively succinylated poly-L-lysine by aqueous extracts of spleens from "responder" (guinea pigs which can develop immune responses to hapten-poly-L-lysine conjugates) and "non-responder" guinea pigs was investigated. The in vivo degradation of H(3)-tagged dinitrophenyl conjugates of these synthetic pol...

In studies of the inhibition in viva of animal viruses by poly-n-lysine, Rubini et al. (1) and Green et al. (2-4) obtained data which suggested that poly-L-lysine is hydrolyzed by the proteolytic enzymes of the allantoic fluid, and that this enzymatic hydrolysis may limit its biological activity. The enzymatic hydrolysis of poly-n-lysine was reported by Katchalski (5) and by Waley and Watson (6...

The aim was to examine the efficiency of a scaffold made poly (L-lactic acid)-co-poly(?-caprolactone), collagen (COL), polyaniline (PANI), and enriched with adipose-derived stem cells (ASCs) as nerve conduit in rat model. P(LLA-CL)-COL-PANI optimized electrospun into tubular-shaped structure. Adipose tissue from 10 Lewis rats harvested for ASCs culture. A total 28 inbred male underwent sciatic ...

Cellular RNA and protein synthesis are required both for interferon synthesis (Heller, 1963; Wagner, 1963) and the expression of the antivirus activity of interferon (Taylor, 1964). The suppression of the antivirus activity of interferon by metabolic inhibitors has been interpreted to mean that interferon acts as a de-repressor for the synthesis of a cellular antivirus protein. While direct pro...