Colorectal cancer (CRC) incidence rates and mortality have been decreasing in the United States. Currently, states in the South have the smallest reduction in CRC mortality. The trends of CRC incidence rates in Georgia in comparison to the United States have not been investigated. We analyzed age-adjusted incidence rates of CRC in Georgia and the United States from 2000 to 2012 using data from ...

PURPOSE The purpose of this study is to describe characteristics of middle-age inpatients' (ages 45-64) fallers and their fall and fall injury risk factors. BACKGROUND Middle-age falls were 42-46% of inpatient falls. Studies related to inpatient falls have not targeted this population. METHODS A 439 retrospective chart review was performed. Middle-age fall and injury rates were compared wit...

BRIC nations – Brazil, Russia, India, and China – represent 40% of the world’s population, including a growing aging population and middle class with an increasing prevalence of chronic disease. Their healthcare systems increasingly rely on prescription drugs, but they differ from most other healthcare systems because healthcare expenditures in BRIC nations have exhibited the highest revenue gr...

Protected areas (PAs) have long been criticized as creations of and for an elite few, where associated costs, but few benefits, are borne by marginalized rural communities. Contrary to predictions of this argument, we found that average human population growth rates on the borders of 306 PAs in 45 countries in Africa and Latin America were nearly double average rural growth, suggesting that PAs...

The quest for new antiparasitic alternatives has led researchers to base their studies on insights into biology, host-parasite interactions and pathogenesis. In this context, proteases and their inhibitors are focused, respectively, as druggable targets and new therapy alternatives. Herein, we proposed to evaluate the in vitro effect of the cysteine protease inhibitor E-64 on Giardia trophozoit...

CONTEXT The mortality numbers and rates of chronic disease are rising faster in developing than in developed countries. This article compares prevailing explanations of population chronic disease trends with theoretical and empirical models of population chronic disease epidemiology and assesses some economic consequences of the growth of chronic diseases in developing countries based on the ex...

BACKGROUND Young people (aged 0-18 years) have been disproportionately affected by pandemic influenza A H1N1 infection. We aimed to analyse paediatric mortality to inform clinical and public health policies for future influenza seasons and pandemics. METHODS All paediatric deaths related to pandemic influenza A H1N1 infection from June 26, 2009, to March 22, 2010 in England were identified th...

Maintenance of sustainable wildlife populations is one of the primary purposes of wildlife management. Thus, it is important to monitor and manage population growth over time. Sensitivity analysis of the long-term (i.e., asymptotic) population growth rate to changes in the vital rates is commonly used in management to identify the vital rates that contribute most to population growth. Yet, dyna...

background: considering the importance of updating information about incidence and mortality of common or fatal cancers and the need for studying the effectiveness   of   changes   in   the   iranian   cancer   registration   system   from pathological based to population based since 2007, the aim of this study was to provide updated population based information on incidence and mortality rates...

The Binary State Speciation and Extinction (BiSSE) model is a branching process based model that allows the diversification rates to be controlled by a binary trait. We develop a general approach, based on the BiSSE model, for predicting pathogenicity in bacterial populations from microsatellites profiling data. A comprehensive approach for predicting pathogenicity in E. coli populations is pro...