Certain miscarriages result from immunologic factors, but there is no clear identification of the precise causes recurrent pregnancy loss (RPL). Miscarriages and RPL can arise a disruption maternal–fetal immune homeostasis. Remodeling maternal uterine spiral arteries one key steps for normal growth development fetus. An adequate oxygen supply necessary correct placentation, it accomplished by p...

UNLABELLED Human reproduction is not considered a highly efficient biological process. Before the end of the first trimester, 30%-50% of conceptions end in spontaneous abortion. Most losses occur at the time of implantation. 15%-20% of clinical pregnancies end in spontaneous abortions. Recurrent pregnancy loss is a frustrating clinical problem both for clinicians and patients. Recurrent pregnan...

Infertility is a condition that affects between one-fifth and one-sixth of couples of reproductive age. It is defined as a reduction in or a lack of ability to reproduce and its cause may lie either in the male or female partner (Stedman, 2006). According to the American Society for Reproductive Medicine, infertility should be considered when pregnancy fails to occur after one year of regular s...

This retrospective study examines the influence of recombinant growth hormone (rGH) and melatonin adjuvants on oocyte numbers, embryo utilization live births arising from 3637 autologous IVF±ICSI treatment cycles undertaken 2376 women across ten years (2011-2020) within a pioneer Australian facility. Despite using an FSH-dosing algorithm enabling maximal doses up to 450 IU for with reduced ovar...

Previous cases reported recurrent all oocytes in repeated cycles were arrested at MI failed to mature after culture and ICSI resulted total nonfertilization. Ionomycin induced first PB extrusion patients with maturation-resistant oocytes. combined assisted oocyte activation (AOA) on MII matured vitro abnormal fertilization no further embryo cleavage potential. The objective of this work was res...