We have investigated adenylate cyclase in ghosts from normal and pathologic human red blood cells. Basic parameters such as specific activity, apparent Michaelis constant (KMapp), and response to effectors: sodium fluoride (NaF), 5'-guanylyl imidodiphosphate (Gpp (NH)p), isoproterenol, and PGE1 were investigated. Basal and NaF-stimulated activities were measured in ghosts from patients with her...

Since 1997, the availability, in haematology laboratories of automated analyzers capable of performing an extended differential blood cell count, including the nucleated red blood cell (NRBC) count, allowed their experimental use to estimate the cell composition of bone marrow fluid. In 1999 we evaluated the Sysmex XE-2100 to detect the clinical usefulness of immature granulocyte (IG) and NRBC ...

body mass index (bmi) has been demonstrated to be associated with serum uric acid (sua) level in many developed countries, however, there is still a lack of large sample study in jiangsu province, one of the most economically developed regions in china, where fat-rich diet is common.through retrospective analysis in healthy subjects, we determined the association of bmi with hyperuricemia risk....

conclusions administration of aeds in general and levetiracetam in particular should be based on attention to pharmacokinetic behavior in terms of monotherapy or polypharmacy. case presentation two cases were studied, one patient was a 32-year-old male and the other was a 14-year-old female. the key words relevant to search topics were surveyed using pubmed (united states national library of me...

objectives: this study aimed to investigate the effect of water-pipe (wp) smoking on hematological parameters of wistar rats. methods: thirty-five young male rats (200-250 g) were randomly assigned to five groups (n=7). the control group was exposed to room air and the experimental groups were exposed to wp smoking, using a special apparatus designed to have the ability to keep the rats for 40 ...

BACKGROUND AND PURPOSE Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of neurological handicap in developing countries. Human umbilical cord blood (hUCB) CD34-positive (CD34⁺) stem cells exhibit the potential for neural repair. We tested the hypothesis that hUCB CD34⁺ stem cells and other cell types [leukocytes and nucleated red blood cells (NRBCs)] that are up-regu...

Objective: Elevated blood glucose may be affect complete count parameters. In this study, we compared the hemogram parameters of healthy individuals and cases with impaired tolerance.
 Method: We examineted 134 patients tolerance 30 cases. Patients files were evaluated retrospectively levels hemoglobin, hematocrit, mean corpuscular volume, red cell, cell distribution wide, platelet leukocy...

The dimorphic blood picture in sideroblastic anemia suggests the coexistence of at least two types of erythrocyte, the populations with the smaller RBCs being responsible for the crucial abnormality, namely the impairment of iron incorporation into protoporphyrin. In a patient with sideroblastic anemia who subsequently developed acute myelocytic leukemia, we found a light and a heavy cell popul...

The dimorphic blood picture in sideroblastic anemia suggests the coexistence of at least two types of erythrocyte, the populations with the smaller RBCs being responsible for the crucial abnormality, namely the impairment of iron incorporation into protoporphyrin. In a patient with sideroblastic anemia who subsequently developed acute myelocytic leukemia, we found a light and a heavy cell popul...