Retinoic acid (RA) is commonly used in vitro to differentiate stem cell populations including adult neural stem cells into neurons; however, the in vivo function of RA during adult neurogenesis remains largely unexplored. We found that depletion of RA in adult mice leads to significantly decreased neuronal differentiation within the granular cell layer of the dentate gyrus. RA contribution to n...

This paper describes a method for building visual “maps” from video data using quantized descriptions of motion. This enables unsupervised classification of scene regions based upon the motion patterns observed within them. Our aim is to recognise generic places using a qualitative representation of the spatial layout of regions with common motion patterns. Such places are characterised by the ...

The malPQ operon, one of the three operons of the maltose regulon, is positively controlled by the product of gene malT. The starting point for malPQ transcription was deduced from experiments which involved a hybridization of in vivo-synthesized malPQ mRNA with adequate DNA probes, followed either by a digestion of nonhybridized DNA (S1 nuclease mapping) or by an extension of the hybridized pr...

This paper is aimed at presenting an innovative ankle rehabilitation device based on a parallel mechanism. A functional analysis and design are described to obtain a device able to guarantee ankle movement while patient's body remains stationary. Human ankle is a challenging context where a series of joints are highly integrated. The proposed rehabilitation device permits a patient with walking...

Plectin is a versatile intermediate filament (IF)-bound cytolinker protein with a variety of differentially spliced isoforms accounting for its multiple functions. One particular isoform, plectin 1b (P1b), remains associated with mitochondria after biochemical fractionation of fibroblasts and cells expressing exogenous P1b. Here, we determined that P1b is inserted into the outer mitochondrial m...

We have investigated the electronic structure of rare-earth tetraborides, $\textrm{RB}_{4}$, using first-principle methods (DFT) implemented in Quantum Espresso (QE). In this article we studied heather-to neglected strong spin-orbit coupling (SOC) effects present these systems on system non-magnetic ground state. The calculations were done under GGA and GGA+SO approximations ultrasoft pseudopot...