AIM Several behavioural correlates of self-injury, aggression and destructive behaviour have been identified in children and young adults with intellectual disabilities. This cross-sectional study aimed to further explore these correlates in very young children with developmental delay. METHODS Parents of 56 children (40 male) under the age of five years (mean age 2 years 10 months) completed...

The purpose of this study was to estimate the relative risk of an injurious fall requiring medical attention in veterans with multiple sclerosis (MS) compared with veterans without MS after controlling for sex, age, and healthcare use. The sample included 195,417 veterans treated at Veterans Health Administration (VHA) facilities in the Northwest United States in fiscal year 2008. We obtained i...

We assessed whether the stereotyped movements (SM) that are a defining characteristic of autism are discriminable from those observed in other disorders, and whether stereotyped self-injurious movements, which are excluded as exemplars of SM in DSM-IV, differ from other SM in severity or in kind. We used the Stereotyped and Self-Injurious Movement Interview to assess self-injurious and other SM...

These experiments indicate that the direct action of x-rays in more powerful doses than can be applied therapeutically is somewhat injurious to tumor cells, but by no means destroys them. Experiment 1 also indicates that the cancer cells establish a resistance to the x-rays after repeated doses. This harmonizes with the experience of clinicians who have succeeded in checking cancerous growths f...

Evidence for synaptopathy, the acute loss of afferent auditory nerve terminals, and degeneration spiral ganglion cells associated with temporary threshold shift (TTS) in traditional laboratory animal models (e.g., mice, guinea pigs) has brought into question whether TTS should be considered a non-injurious form noise impact marine mammals. Laboratory studies also demonstrate that both neuropath...