Protocadherin 19 (Pcdh19) is an X-linked gene belonging to the protocadherin superfamily, whose members are predominantly expressed in the central nervous system and have been implicated in cell-cell adhesion, axon guidance and dendrite self-avoidance. Heterozygous loss-of-function mutations in humans result in the childhood epilepsy disorder PCDH19 Girls Clustering Epilepsy (PCDH19 GCE) indica...

Due to popular use of internet and fast progress of communications technology, the researches related to GIS in environmental models is being focused to use Geospatial Information System (GIS) in a Service Oriented Architecture (SOA). In this architecture, the geo service requesters can access the provided geo-services through the communication network by using client/server method. Effectivene...

World-system dynamics are re-conceptualized as inter-societal systems with some de-emphasis on the notions of core, periphery, and semi-periphery. This tri-part division has been useful in forcing sociology to rethink macrolevel sociological analysis and in establishing the importance of considering inter-societal systems as a fundamental unit of human social organization, but this Weberian-lik...

This paper presents a number of new techniques for parallelizing geo-spatial database systems and discusses their implementation in the Paradise object-relational database system. The effectiveness of these techniques is demonstrated using a variety of complex geo-spatial queries over a 120 GB global geo-spatial data set.

PURPOSE The epidermal growth factor receptor (EGFR) autocrine signaling pathway is involved in cancer development and progression. EGFR inhibitors such as C225 (cetuximab), a chimeric human-mouse anti-EGFR monoclonal antibody, and ZD1839 (gefitinib), a small molecule EGFR-selective tyrosine kinase inhibitor, are in advanced clinical development. The potential emergence of cancer cell resistance...

Die Anwendung Remote Task Control entstand in Zusammenarbeit der Firmen HORSCH und geo-konzept im Forschungsprojekt Geo Farm und ermöglicht eine durchgängig automatisierte Prozesskette von der Bereitstellung und Archivierung georeferenzierter Applikationskarten und Datenübertragung zur Landmaschine bis zur Ausführung und Dokumentation des variablen Applikationsprozesses im Feld. Das Projekt Geo...

We describe a basic Geo-coding service encompassing a geo-parsing tool and integrated digital gazetteer service. The development of a geo-parser comes from the need to explicitly georeference large resource collections such as the Statistical Accounts of Scotland which currently only contain implicit georeferences in the form of placennames thus making such collections inherently geographically...

We describe a basic Geo-coding service encompassing a geo-parsing tool and integrated digital gazetteer service. The development of a geo-parser comes from the need to explicitly georeference large resource collections such as the Statistical Accounts of Scotland which currently only contain implicit georeferences in the form of placennames thus making such collections inherently geographically...

Massive amount of data that are geo-tagged and associated with text information are being generated at an unprecedented scale. These geo-textual data cover a wide range of topics. Users are interested in receiving up-to-date geo-textual objects (e.g., geo-tagged Tweets) such that their locations meet users’ need and their texts are interesting to users. For example, a user may want to be update...