Synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. Globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. Vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...

Ovarian cancer is the most lethal gynecologic malignancy. The surface epithelial tumor is the most common type of ovarian cancer. Among these, the mucinous tumors account for 10-15% of ovarian tumors. Mucinous ovarian tumors are among the most difficult ovarian neoplasms for surgical pathologists to interpret. Mucinous tumors sometimes coexist with other surface epithelial tumors. Therefore, ma...

Objective(s): The Muller cell is the principal glial cell of the vertebrate retina. The expression of Glial fibrillary acidic protein (GFAP) in the Muller cells was used as a cellular marker for retinal damage. This study was done to evaluate the effect of gestational diabetes on retinal Muller cells in rat's offspring. Materials and Methods: In this experimental study, 12 Wistar rat dams were ...

Many clinical entities may be associated with the development of peripheral retinal neovascularization. In this paper, we review the mechanisms of normal and abnormal angiogenesis in the retina. Specific disease entities associated with peripheral proliferative retinopathies are discussed. These include vascular disease with ischemia, inflammatory diseases with possible ischemia and a variety o...

Thymomas and thymic carcinomas are rare mediastinal neoplasms arising from epithelial cells, the presence of synchronous or metachronous primary in a single patient is an extremely event. Thymoma patients appear to have inherent predisposition toward developing additional neoplasms. This additionally presents diagnostic challenge, revealing importance multidisciplinary expertise management thes...

The discovery that certain tumors may be in duced in certain species by viruses led to attempts to transmit mammalian tumors by injection of cell-free preparations. Taylor and co-workers (7, 8) claimed success with such material, but others failed to corroborate their findings (†̃2, 9). We are aware of no previous report of transmission of a mammalian neoplasm by injection of isolated cytoplas...

The word “cancer” is perhaps the most feared word in our language. This is largely due to the aggressive nature of this disease, but also because so much is yet unknown about this disease. This lecture will provide an overview of our current understanding of cancer, or more generally, neoplasia. Neoplasia can be defined as a clonal proliferation of cells with somatic genetic alterations and abe...