retinoblastoma is the most common intraocular neoplasm in children. glial tumor of the retina and optic nerve head are considered to be congenital and are therefore classified as hamartomas. concurrent occurrence of these tumors in one eye is uncommon and by reviewing the studies, a few cases have been reported. we report a 9 years old boy with eye enucleation and concurrent occurrence of retin...

BACKGROUND Neoplasms of the retinal pigment epithelium (RPE) are rare, and little is known about their clinical variations, clinical course, and prognosis. Although most are benign, they can simulate choroidal melanoma. OBJECTIVES To evaluate the clinical characteristics, management, pathological features, and prognosis of acquired neoplasms of the RPE (adenoma and adenocarcinoma) and to defi...

OBJECTIVE To report the clinical and histopathologic findings of retinal astrocytic tumors that showed progressive growth in four patients with tuberous sclerosis complex (TSC). METHODS Four young children each developed an enlarging retinal neoplasm that eventually necessitated enucleation of the affected eye. The systemic findings, clinical course, and histopathologic findings were reviewed...

Purpose: Ocular neoplasms, both primary and metastatic, may present with visual disturbance or vision loss often are asymptomatic. Clinical examination demonstrate leukocoria, abnormal pupillary light reflex, a mass lesion without retinal detachment hemorrhage. Retinoblastoma in children uveal melanoma ocular metastases adults the most important malignant neoplasms referred for imaging to aid d...

vitreous cavity. Strong glial fibrillary acidic protein positivity confirms the diagnosis. Thickening of the vessel walls, perivascular pigment, intralesional cysts, and calcareous deposits (calcospherites) are also detectable. Massive retinal gliosis is characteristically encountered in phthisical eyes after trauma, surgery, or inflammation and in other conditions such as retinopathy of premat...

Background Degenerative retinal diseases, including age related macular degeneration, glaucoma, and hereditary retinal dystrophies are major causes of blindness. The principal defect in these diseases is cell loss which is amenable to both cell based neuroprotective and neuroregenerative therapies. To briefly review the lines of research and potential candidates for cell based therapies among ...

Neoplasms of retinal pigment epithelium are rare and must be differentiated from choroidal melanoma. The possibility of a metastatic disease with possible primary sites as lung, breast, or kidney should be ruled out. Herein we report a case of adenocarcinoma arising from the RPE with a lung lesion suspicious of bronchogenic carcinoma. In this paper, ocular symptoms were the first sign of a syst...