Suitable alternatives are made for damaged or diseased organs and tissues in tissue engineering by combining cellular and molecular biology with materials and mechanical engineering. Fibrin is a critical blood component responsible for homeostasis, used extensively as a biopolymer scaffold in tissue engineering. This study summarizes the latest developments in organ and tissue regeneration usin...

Platelet-rich fibrin (PRF) has a lot of benefits in the process healing. The new generation PRF, namely advanced PRF plus (A-PRF+), different structure and more growth factors compared to Advanced (A-PRF), before A-PRF+. Objectives:To effects A-PRF A-PRF+ on IIB degree burn. Methods: This experimental study used 20 male Sprague Dawley rats. All rats were given burn divided into four groups. Gro...

Mucosal fenestration associated with maxillary first molar is rare but challenging to treat when there loss of marginal bone along buccally oriented root angulation. The exposed within the oral cavity large mucosal defect makes it susceptible plaque accumulation and infection. This case report showcases management mesiobuccal Left Maxillary by resection Platelet rich fibrin membrane.

The effect of autologous platelet rich fibrin (PRF), a second generation platelet product, on the healing of experimental articular cartilage lesions was evaluated in an animal model. Full thickness cartilage lesions with a diameter of 6 mm and depth of 5 mm were created in the weight bearing area of femoral condyles of both hind limbs in 12 adult mixed breed dogs. Defects in the left hind limb...

UNLABELLED This study evaluated the effect of periarticular pain cocktail, platelet-rich plasma, or fibrin sealant injections on blood loss, transfusion rate, and hospital costs after total knee arthroplasty. A retrospective review of 400 patients undergoing primary total knee arthroplasty with one of the different periarticular treatments as stated above was performed. Postoperative blood loss...

Now a days Platelet-Rich Fibrin (PRF) is gaining more attention for obtaining periodontal regeneration. Platelet-rich fibrin (PRF) is considered a second-generation platelet concentrate that is widely used in osseous regeneration. The purpose of this case report is to present clinical and radiographic results of an intrabony periodontal defect treated with PRF. After surgical treatment with aut...

The formation of thrombi in vivo includes the activation of both platelets and the coagulation cascade. Conventional thrombolytic therapy is primarily directed toward the dissolution of fibrin. To evaluate the possibility that platelet activity impairs the lysis of thrombi, we studied the effects of aspirin and platelet-deaggregating prostaglandin El on thrombolysis with urokinase. Combined pla...