Introduction: Minor salivary gland tumors are relatively rare, but have a higher chance of malignancy than major salivary gland tumors. The palate appears to be the most commonly involved site. The most frequent benign tumor is the pleomorphic adenoma. Case report: We report a case of a pleomorphic adenoma, which occurred in the hard and soft palate of a 34-year-old female and presented as an a...

Salivary gland neoplasms have always been an field of interest for head neck and tumors because of its diversity in histogenesis and morphogenesis. Its of keen interest that all benign tumors arise from major salivary glands whereas on the other side all malignant arise from minor salivary glands. Reason for the above criteria can be understood only when a complete knowledge and understanding o...

background: in cancers of prostate, breast, oropharynx, lung, hypopharynx and skin, human tissue kallikreins has been demonstrated as a main role in these problems. there are many research works in which some human tissue kallikreins are expressed in salivary glands. in the present study, the main goal was to determine expression of human tissue kallikreins 4, 8, 10, 11 and 13 in pleomorphic ad...

Polymorphous low‐grade adenocarcinoma (PLGA) is difficult to diagnose due to its indolent clinical presentation and due to its morphological diversity that includes several microscopic patterns. Distinguishing it from high‐grade tumors of salivary gland is important, as the management and prognosis of this tumor differ. We report a considerably rare case of PLGA in retromolar area highlighting ...

The monitoring of the patients after salivary gland tumors surgery is an important clinical issue. Still imperfect diagnostic procedures also remain a challenge for searching new sensitive and specific biomarkers of neoplastic processes in salivary glands. The aim of the presented study was an the assessment of the activity of HEX, with its isoforms HEX-A and HEX-B, GLU, GAL, MAN and FUC in sal...

BACKGROUND The primary objective of this study is to describe variations in incidence rates, resection rates, and types of surgical ablations performed on patients diagnosed with major salivary gland cancers in Ontario. METHODS All major salivary gland cancer cases in Ontario (2003-2010) were identified from the Ontario Cancer Registry (n = 1,241). Variations in incidence rates, resection rat...

Introdouction: Mucoepidermoid carcinoma (MEC) is one of the most common salivary gland malignancies. The prevalence of salivary gland tumors varies in different geographic areas. In this report, we evaluated the prevalence of MEC in Iran and compared it with that previously reported in other countries. Materials and methods: The files of oral pathology, Shahid Beheshti University of Medical ...

salivary gland tumors are rare in children and, when they do arise, they mainly affect the major salivary glands. minor salivary gland tumors are rare in children and are responsible for less than 10% of the cases. pleomorphic adenoma is the most common tumor of the salivary glands. the most common sites of pleomorphic adenoma of the minor salivary glands are the palates, followed by the lips a...

Introduction: Natural killer (NK) cells, of which CD56 is a specific marker, play an important role in host defense against tumors. Cancer stem cells, of which aldehyde dehydrogenase isoform 1 (ALDH1) is an immunohistochemical marker, are a group of tumorigenic cells which are involved in migration and tumor recurrences. We aimed to evaluate the expression of ALDH1 and CD56 in common salivary g...