Experiments were performed to determine whether acetylcholine affects the sympathetic activation of the cutaneous veins of the dog. Changes in isometric tension of saphenous vein strips were recorded at 37°C in an organ bath. Addition of acetylcholine at 1CH to 10~ g/ml did not affect basal tension, but larger doses (5 X 1CH to 5 X 1CH g/ml) caused a contraction of the strips which varied from ...

Purpose: This study aimed at clarifying the changes in treatments for primary varicose veins in Japan. Methods: A questionnaire was mailed to the members of the Japanese Society of Phlebology. The contents of the survey covered the treatment and treatment strategy of varicose vein cases in 2013. The results were examined and compared with the results of previous surveys conducted by the aforesa...

OBJECTIVE In this histological study, the lateral saphenous vein of the goat was treated using a laser fibre to which a tulip-shaped, self-expandable catheter had been fixed to achieve endovenous laser ablation (EVLA). The catheter centres the laser fibre in the vein preventing direct contact with the vein wall. This study aims to establish whether prevention of direct contact between the fibre...

INTRODUCTION Saphenous vein grafting is still widely used to revascularize ischemic myocardium. The effectiveness of this procedure is limited by neointima formation and accelerated atherosclerosis, which frequently leads to graft occlusion. A better understanding of this process is important to clarify the mechanisms of vein graft disease and to aid in the formulation of strategies for prevent...

Epigenetic mechanisms of gene regulation in context of cardiovascular diseases are of considerable interest. So far, our current knowledge of the DNA methylation profiles for atherosclerosis affected and healthy human vascular tissues is still limited. Using the Illumina Infinium Human Methylation27 BeadChip, we performed a genome-wide analysis of DNA methylation in right coronary artery in the...

OBJECTIVE The theory of primary venous dilatation leading to secondary valvular incompetence and varicose vein formation has received more attention nowadays. Although many studies have investigated the role of the main components of the venous wall in the development of varicose veins, the leading cause remains unknown. The present study was designed to establish the role of smooth muscle cell...

OBJECTIVE To produce a comprehensive anatomical and hemodynamic ultrasound scan mapping of the whole limb in patients with primary varicose veins (VVs). DESIGN An analysis of venous duplex scans performed on patients referred for treatment of primary VVs. METHODS A total of 2036 limbs were evaluated, looking for the origin of VVs in the saphenous systems and in the perforating vein (PV) sys...

AIM To explore the correlation between perforating vein incompetence and the extent of great saphenous vein insufficiency according to Hach. METHODS Duplex ultrasound was used to determine the number of incompetent perforators and diameter of perforating veins, and the level of great saphenous vein reflux and the presence or absence of deep reflux in 118 lower limbs (59 patients). There were ...

INTRODUCTION: The article is devoted to such an urgent problem as the choice of most effective and safe method treatment thrombophlebitis saphenous veins lower extremities. This pathology one common in vascular surgery. Left untreated, vein can lead a life-threatening complication pulmonary embolism. main tasks that surgeon faces during are prevent progression disease, relieve symptoms reduce l...