Background. Remimazolam, a benzodiazepine sedative with clinical advantages, is used for anesthesia during GI endoscopy. However, the accurate dosage remains understudied. This study aims to investigate 90% effective dose (ED90) of remimazolam in inhibiting responses upper endoscopy insertion and evaluate its efficacy safety endoscopic diagnosis treatment. Methods. A total 54 adult patients und...

Today many surgical procedures involving head and neck areas can be performed under local anesthesia and intravenous sedation. The authors add to this list the sagittal osteotomies of the mandibular rami, thereby avoiding the need for general anesthesia and a hospital stay. The authors designed a protocol to be followed in a multicenter study (Milan and Barcelona) and applied it in 35 clinical ...

Dental fear and anxiety is a common problem in pediatric patients. There is considerable variation in techniques used to manage them. Various sedation techniques using many different anesthetic agents have gained considerable popularity over the past few years. Children are not little adults; they differ physically, psychologically, and emotionally. The purpose of this review is to survey recen...

Abstract Introduction Transcatheter aortic-valve replacement (TAVR) procedure has been simplified, being now a less-invasive minimalist strategy the standard of treatment. Therefore, length hospitalization decreased, and early-discharge (ED) (<72 hour) protocols are in development. Lately, additional techniques to optimize TAVR have arisen, such as use radial approach secondary access, c...

TO THE EDITOR: We read with great interest the article by Quill and colleagues (1), which presented and discussed 3 categories of palliative sedation: ordinary sedation, proportionate palliative sedation (PPS), and palliative sedation to unconsciousness (PSU). One notion shared by these practices, and by all attempts to justify sedation, is that the degree of sedation should match the symptoms—...

Sedation and analgesia are a constant challenging issue in paediatric intensive care units, for ethical reasons among others. Basically, goals and available treatments in that context do not differ from those in adults. For instance, while we propose midazolam as the first choice benzodiazepine, there is no evidence for encouraging the use of one morphinomimetic rather than others in children. ...

how to cite this article: fallah r, fadavi n, behdad sh, fallah tafti m. efficacy of chloral hydrate-hydroxyzine and chloral hydrate-midazolam in pediatric magnetic resonance imaging sedation. iran j child neurol. 2014 spring 8(2):11-17. objective magnetic resonance imaging (mri) is a useful diagnostic tool for the evaluation of congenital or acquired brain lesions. but, in all of less than 8-y...

The purpose of this study was to evaluate the effects of flumazenil (1 mg i.v.) on the ventilatory response of premedicated patients receiving a continuous infusion of midazolam for sedation. After assessing baseline ventilatory function using a modified Read rebreathing method for determining hypercapnic ventilatory drive, 16 healthy outpatients were administered fentanyl, 50 micrograms i.v., ...

RATIONALE Levator resection has become a routine procedure for patients with severe Marcus Gunn jaw-winking synkinesis (MGJWS). To optimize the surgical outcome, adult patients need to be kept awake, or easily aroused and responsive to verbal commands during the operation. However, levator resection is commonly performed under general anesthesia in pediatric patients. In the present case, we de...