The XX/XY sex-determination system is one of the most familiar sex-determination systems and is found in human beings and most other mammals. In this sex-determination system, females have two sex chromosomes of the same kind, while males have two distinct sex chromosomes. Hence, if certain characteristics are due to genes linked to the Y chromosome, then they are only associated to the males. ...

Papers in this Thesis Paper I " Role of MAO-A genotype & psychosocial factors in male adolescent criminal activity " , Paper II " Role of the serotonin transporter gene and family function in adolescent alcohol consumption " , Paper III " Development of depression: sex and the interaction between environment and promoter polymorphism of the serotonin transporter gene " , Paper IV " Adolescent g...

A multitype bisexual branching process is considered to model the behaviour of a Y-linked gene with two genotypes in a two-sex population. It is assumed perfect fidelity mating with preference of females for the males carrying certain allele of the gene. Under these assumptions, we study the rate of growth of each genotype on the event of non-extinction. The rate of growth of a genotype may dep...

Sex steroids are of profound importance for several physiological processes including reproduction, growth, and maintenance of skeletal integrity. Serum levels of sex steroids are associated with bone mineral density (BMD) and have been shown to be predictive of fracture risk in older people. Sex steroid levels in serum, and also BMD and fracture risk, are under genetic control. Catechol-O-meth...

Systems with genetic variation for the primary sex ratio are important for testing sex-ratio theory and for understanding how this variation is maintained. Evidence is presented for heritable variation of the primary sex ratio in the harpacticoid copepod Tigriopus californicus. Variation in the primary sex ratio among families cannot be accounted for by Mendelian segregation of sex chromosomes....

Objective(s): Asthma, the most frequent chronic respiratory disease, results from a complex interaction between multiple genes and environmental factors. To date, more than 100 candidate genes and single nucleotide polymorphisms (SNPs) have been reported to be associated with asthma. One of the discovered genes related to asthma is ADAM33. However, the relationship between ADAM33 gene polymorph...

It is now clear that mechanisms of sex determination are extraordinarily labile, with considerable variation across all taxonomic levels. This variation is often expressed through differences in the genetic system (XX-XY, XX-XO, haplodiploidy, and so on). Why there is so much variation in such a seemingly fundamental process has attracted much attention, with recent ideas concentrating on the p...