INTRODUCTION Undifferentiated arthritis (UA) has a variable disease course; 40 to 50% of UA patients remit spontaneously, while 30% develop rheumatoid arthritis (RA). Identifying the UA patients who will develop RA is essential to initiate early disease-modifying anti-rheumatic drug (DMARD) therapy. Although the presence of bone erosions at baseline is predictive for a severe destructive diseas...

Multiple skull erosions which simulated bone mestatases developed in a 54-year-old patient who had been treated for favus by radiotherapy 40 years earlier. Radiation necrosis should be recognized and differentiated from defects and erosions due to malignant or infectious process in order to prevent unnecessary procedures and treatment.

The hands of 10 patients with rheumatoid arthritis were investigated with diphosphonate scanning and radiology. Increased uptake of isotope can be associated with some erosions but not all and also reflects other processes more linked to acute inflammatory areas unassociated with the development of erosions. If the latter are the hallmark of active rheumatoid arthritis then bone scans are not.

Takeuchi et al demonstrate an additional inhibitory effect on the progression of bone erosions in rheumatoid arthritis (RA) with the addition to methotrexate of an anti-receptor activator of nuclear factor kappa-B ligand (RANKL) antibody, denosumab, confirming results already reported 8 years ago by Cohen and colleagues. Insufficient inhibition of structural joint damage by diseasemodifying ant...

Reports on healing of erosions in rheumatoid arthritis are rare. However, it is expected that repair of erosions should be seen more often during the period of extensive use of disease modifying antirheumatic drugs, especially in patients who experience sustained remission. Two such cases are described.

Psoriasis and pemphigus vulgaris are two inflammatory and autoimmune diseases. Their concomitant occurrence in one patient is very rare. We describe a 57-year-old patient with a history of severe plaque type psoriasis for 2 years. After a few months, he presented with disseminated bullae and mucosal erosions which were documented as pemphigus vulgaris. Both of the diseases were successfully con...

Porous materials are lightweight, flexible and resistant to hairline cracks, so today with the development of technology porous structure produced for use in various industries. This structure widely use in beams, plates and shells. The purpose of this paper is to investigate the effect of porosity in axial symmetry in bending and buckling load sheet for analysis. For this purpose, a circular p...

in this work, laser bending of perforated sheets has been investigated numerically. laser bending of perforated sheets is more complicated than non-perforated sheets due to their complex geometries. in this paper, laser bending of perforated sheets is studied numerically in the form of thermo-mechanical analysis with abaqus/implicit code. for this purpose, the effects of process and sheet param...

Previous studies have shown that the development of mam mary alveolar lesions (MALs) precedes the emergence of overt mammary tumors in high-breast-cancer strains of mice, such as Rill, that are infected with exogenous murine mammary tumor virus. We cultured MAL-containing whole mammary glands from 7-month-old nulliparous Rill mice for 8 days (Days 0 to 8) in a serum-free medium that contained i...