OBJECTIVES To systematically analyse the literature on reported adverse events (AEs) of intravenous pulse glucocorticoids (GCs) (≥ 250 mg prednisone equivalent) for inflammatory diseases. METHODS A literature search was done using PubMed, Embase, and Cochrane databases. Studies were selected by two reviewers (NAMS and ND). Available data on the prevalence of GC-related AEs in patients with in...

BACKGROUND There is strong evidence that locally secreted cytokines control the implantation process and can cause implantation failure. Uterine flushing fluids were analysed to determine their concentrations of leukaemia inhibitory factor (LIF) and tumour necrosis factor (TNF). METHODS AND RESULTS We began by flushing the uterine cavities of 33 infertile patients on day 26 of two consecutive...

This study investigated the effect of dietary supplementation with calcium salts of fatty acids using 48 Afshari ewes randomly allocated to four treatments. All groups used in flushing period and only the source of energy were different between rations. The ewes were divided into four groups: A-barely grain; group B-received 5% of CSFA with source of flaxseed oil (w3); group C-received 5% of CS...

An increasing number of integrated optical and acoustic intravascular imaging systems have been developed and hold great promise for accurately diagnosing vulnerable plaques and guiding atherosclerosis treatment. However, in any intravascular environment, the vascular lumen is filled with blood, a high-scattering source for optical and high-frequency ultrasound signals. Blood must be flushed aw...

Numerical modeling of sediment transport in reservoirs, especially for sudden events such as flushing, is still a challenging research topic. In the present study, sediment transport and sediment flushing are simulated for a Peruvian reservoir. Situated in the Peruvian Andes, the watershed is affected by high erosion rates and the river carries high amounts of suspended sediment whose estimated...

Treatment with niacin effectively improves multiple lipid parameters and cardiovascular outcomes. Widespread use of niacin, however, is limited by flushing, which is mediated primarily by prostaglandin D2 (PGD2). Laropiprant is a selective PGD2 receptor 1 (DP1) antagonist that reduces objective measures of niacin-induced flushing symptoms upon initiation of therapy and with more chronic use. Re...

The purpose of the present study was to determine the chronology of the pre-implantation embryonic development in Myocastor coypus (coypu). It was carried out by daily colpocytological examination and controlled mating of 33 females. Oocytes and embryos were obtained by flushing from day 0 to day 10 post-coitus (p.c.). On day 1 p.c., oocytes predominated whereas on day 2 p.c. zygotes were predo...

The objective of this study was to assess the LIF (leukemia inhibitory factor) concentration in uterine flushing and serum (ELISA) of women with proven fertility, infertile women and women with recurrent miscarriage. In addition, progesterone level was determined in serum. A decreased production of LIF in the uterine microenvironment was found in states of impaired fertility. With a cut-off poi...

the objective of this study was to determine and compare cystatin c changes before and after radiotherapy in patients with stomach cancer who were candidate for radiotherapy. this study was conducted as a prospective cohort one. eighteen patients with definite diagnosis of stomach cancer under treatment by radiotherapy who presented to radiotherapy-oncology center of imam hossein hospital, tehr...