Sex differences exist in vulnerability, symptoms, and treatment of many neuropsychiatric disorders. In this review, we discuss both preclinical and clinical research that investigates how sex influences depression endophenotypes at the behavioral, neuroendocrine, and neural levels across the lifespan. Chronic exposure to stress is a risk factor for depression and we discuss how stress during th...

The perseverative cognition hypothesis (PCH) posits that perseveration, defined as the repetitive or sustained activation of cognitive representations of a real or imagined stressor, is a primary mechanism linking psychological (or stress) vulnerability with poor health and disease. Resting vagally mediated heart rate variability (vmHRV) is an important indicator of self-regulatory abilities, s...

Predicting the individual vulnerability to immune mediated disease is one of the main challenges of modern biomedical research. However, the question of individual behavioral and physiological characteristics that might predict this vulnerability has been subject of research and debate for a long time. This paper will argue that animal models aimed at individual vulnerability should consider th...

Javier R. Caso [email protected] PhD, Biological Sci 2007 Postdoctoral researcher Dpto. Farmacología. Fac. Medicina. UCM Stress-induced gastrointestinal processes. Beatriz Gómez Pérez-Nievas. [email protected] Bsc Pharmacy 2004. DEA 2006 Predoctoral researcher, PhD student Dpto. Farmacología. Fac. Medicina. UCM Markers of vulnerability of stress response. Molecular mechanisms of stress-induce...

More specifically, a decomposition algorithm that produces several disjoint paths, the union of which results in the original graph has been developed and VDM specification of the process is described. The advantage of specifying the algorithm in VDM is to introduce rigour and to eliminate inconsistencies and ambiguity, facilitating code development for the purpose of automated implementation o...

This study presents a new visualization tool for classification of satellite imagery. Visualization of feature space allows exploration of patterns in the image data and insight into the classification process and related uncertainty. Visual Data Mining provides added value to image classifications as the user can be involved in the classification process providing increased confidence in and u...

background: the stresses elderly face in various situations are different from those faced by other age groups. they are at a stage in life where they may face extended and critical health problems. in general, aging adults are vulnerable to the harmful effects of a negative stressor factors. this study was conducted to evaluate the effects of precede model-based educational program on level of...

We present an approach to the speci cation of required external non-determinism: the willingness of a component to respond to a number of external action requests, using a language, COMMUNITY, which provides both permission and willingness guards on actions. This enables a program-like declaration of required non-determinism, in contrast to the use of a branching-time temporal logic. We give a ...

Severe and chronic stress may interfere with adolescent neuronal plasticity that turns the juvenile brain into an adult brain increasing the vulnerability to develop anxiety disorders. It is well-known from adult stress research that there is a large individual differentiation in stress vulnerability. The current study is aimed at the individual resilience and vulnerability to adolescent social...