The structure of the testis of the goby Glossogobius olivaceus was histologically studied. The testis was a small elongate organ and was semicircular or reverse triangle in shape in cross section. The testis was composed of two main parts; peripheral seminiferous region and central large glandular region. Seminiferous region was mainly composed of seminiferous lobules. The cyst of germ cells co...

This review will focus the roles of TNF-alpha, IL-1 alpha, and IL-1 beta in the mammalian testis and in two testicular pathologies, testicular torsion and orchitis. TNF alpha in the testis is produced by round spermatids, pachytene spermatocytes, and testicular macrophages. The type 1 TNF receptor has been found on Sertoli and Leydig cells and numerous studies suggest a paracrine mode of action...

At the apical tip of the Drosophila testis, germline and somatic stem cells surround a cluster of somatic cells called the hub. Hub cells produce a self-renewal factor, Unpaired (Upd), that activates the JAK-STAT pathway in adjacent stem cells to regulate stem cell behavior. Therefore, apical hub cells are a critical component of the stem cell niche in the testis. In the course of a screen to i...

BACKGROUND Reptiles are phylogenically important group of organisms as mammals have evolved from them. Wall lizard testis exhibits clearly distinct morphology during various phases of a reproductive cycle making them an interesting model to study regulation of spermatogenesis. Studies on reptile spermatogenesis are negligible hence this study will prove to be an important resource. METHODOLOG...

Testis of Hemidactylus flaviviridis, commonly known as Indian wall lizard, displays a lack of cellular and metabolic activity in regressed phase of testis during non-breeding season of the year. Retracted Sertoli cells (Sc), fibroid myoid cells and pre-meiotic resting spermatogonia are observed in such testis. This situation is akin to certain forms of infertility in men where hormone supplemen...

23 Iron is essential for male fertility and disruptions in iron balance lead to impairment of testicular 24 function. The divalent metal transporter DMT1 is a key modulator of transferrin and non-transferrin 25 bound iron homeostasis. As a first step in determining the role of DMT1 in the testis, we have 26 determined the pattern of DMT1 expression in the developing and adult rat testis. Northe...

In all vertebrates sex determination is the step at which development of a testis or ovary is initiated in the bipotential gonad. Although Mus musculus and the red-eared slider turtle, Trachemys scripta, use different mechanisms to initiate organogenesis of the testis (the Y-linked gene, Sry, in the mouse vs. the incubation temperature of the egg in the turtle), the structure of the adult testi...