Objective: Doxorubicin (DOX) is a broad spectrum chemotherapeutic agent used in the treatment of several malignancies. The use of DOX in clinical chemotherapy has been restricted due to its diverse toxicities, including reproductive toxicity. Crataegus monogyna (C. monogyna) is one of the oldest medicinal plants that have been shown to be cytoprotective because of scavenging free radicals. The ...

This study delves into the critical issue of repression Afghan women as mentioned in Khalid Hosseini's novel "A Thousand Splendid Suns.” It aims to ensure that by putting perspective women's experiences a particular combination historical, political, cultural factors. Considering this book, research argues circumstances violence and war Afghanistan during an important phase its history exacerba...

background: the aim of this study was optimization of the polyfect gene delivery method of pcdna3.1 expression vector transfected with the mouse pdx-1 gene in three different kinds of mesenchymal stem cells and hepa cells as well as comparison of transfection efficiency leading to expression of the mentioned gene in the cell types used. materials and methods: rat bone marrow-derived mesenchymal...

Drug-drug interactions (DDIs) are defined as clinically meaningful alterations in the exposure and response to a drug (called object drug) that has occurred as a result of the co-administration of another drug (called precipitant drug). According a 2011 study, drug-drug interactions (DDIs) are responsible for roughly 220,000 hospital admissions per year (Percha and Altman 2013). However, this n...

Abstract Repercussions of global crises can often be seen in the fact that many legal issues arise or become even more complex, while this is also true when speaking about crisis caused by COVID-19 pandemic. Certainly, analysis effects such great importance during peak crisis, but afterwards, context shaped (previous) crisis. In light mentioned, widely present issue discrimination world work ha...

Cyclophosphamide (CP) is extensively used as an antineoplastic agent for treatment of various cancers, as well as an immunosuppressive agent. However, despite its wide spectrum of clinical uses, CP is known to cause several adverse effects including reproductive toxicity in humans and experimental animals. Crataegus monogyna is one of the oldest medicinal plant has been shown to be cytoprotecti...